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A recombinant DNA and vaccinia virus prime–boost regimen induces potent long-term T-cell responses to HCV in BALB/c mice

To explore the best prime–boost regimen and evaluate the T-cellular response memory against HCV, we constructed two DNA vaccine candidates (pVRC-CE1E2 and pAAV-CE1E2) and two recombinant viruses (rTTV-E1E2 and rAAV-E1E2) and then assessed the immune response to different prime–boost patterns in BALB...

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Detalles Bibliográficos
Autores principales: Deng, Yao, Zhang, Ke, Tan, Wenjie, Wang, Yue, Chen, Hong, Wu, Xiaobing, Ruan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115398/
https://www.ncbi.nlm.nih.gov/pubmed/19356609
http://dx.doi.org/10.1016/j.vaccine.2009.02.003