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ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells

Despite new agent development and short-term benefits in patients with colorectal cancer (CRC), metastatic CRC cure rates have not improved due to high rates of 5-fluorouracil (5-FU)/leucovorin/oxaliplatin (FOLFOX)-resistance and a clinical therapeutic plateau. At the same time, this treatment regim...

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Detalles Bibliográficos
Autores principales:	Narayan, Satya, Ramisetti, Srinivasa, Jaiswal, Aruna S., Law, Brian K., Singh-Pillay, Ashona, Singh, Parvesh, Amin, Shantu, Sharma, Arun K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Masson SAS. 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115410/ https://www.ncbi.nlm.nih.gov/pubmed/30384048 http://dx.doi.org/10.1016/j.ejmech.2018.10.052

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