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Optimization of xanthatin extraction from Xanthium spinosum L. and its cytotoxic, anti-angiogenesis and antiviral properties

The aqueous extraction of the sesquiterpene lactone xanthatin from Xanthium spinosum L. favours the conversion of xanthinin (1) to xanthatin (2) via the loss of acetic acid. The cytotoxic (Hep-G2 and L1210 human cell lines) and antiviral activities of isolated xanthatin are established. This natural...

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Detalles Bibliográficos
Autores principales:	Romero, M., Zanuy, M., Rosell, E., Cascante, M., Piulats, J., Font-Bardia, M., Balzarini, J., De Clerq, E., Pujol, M.D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Masson SAS. 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115430/ https://www.ncbi.nlm.nih.gov/pubmed/25481815 http://dx.doi.org/10.1016/j.ejmech.2014.11.060

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