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Intranasal Protollin-formulated recombinant SARS S-protein elicits respiratory and serum neutralizing antibodies and protection in mice

The feasibility of developing a prophylactic vaccine against SARS was assessed by comparing the immune responses elicited by immunizing mice with a recombinant SARS spike glycoprotein (S-protein) formulated with different adjuvants, given by different routes. In both young and aged mice, an intranas...

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Detalles Bibliográficos
Autores principales:	Hu, Mary C., Jones, Taff, Kenney, Richard T., Barnard, Dale L., Burt, David S., Lowell, George H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2007
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115497/ https://www.ncbi.nlm.nih.gov/pubmed/17640780 http://dx.doi.org/10.1016/j.vaccine.2007.06.017

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