Pharmacokinetics, toxicity of nasal cilia and immunomodulating effects in Sprague–Dawley rats following intranasal delivery of thymopentin with or without absorption enhancers

Thymopentin (TP 5), a synthetic pentapeptide, has been used in clinic as a modulator for immnuodeficiencies through intramuscular administration. The objectives of this study was to investigate the pharmacokinetics using normal rats and toxicity of nasal cilia as well as immunomodulating effects usi...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Lu, Wan-Liang, Liang, Gong-Wen, Wu, Ke-Chun, Zhang, Chun-Guang, Zhang, Xuan, Wang, Jian-Cheng, Zhang, Hua, Wang, Xue-Qing, Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115518/
https://www.ncbi.nlm.nih.gov/pubmed/16242213
http://dx.doi.org/10.1016/j.peptides.2005.09.008

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