Cargando…

A truncated fragment of Ov-ASP-1 consisting of the core pathogenesis-related-1 (PR-1) domain maintains adjuvanticity as the full-length protein

The Onchocerca volvulus activation-associated secreted protein-1 (Ov-ASP-1) has good adjuvanticity for a variety of antigens and vaccines, probably due to its ability activate antigen-processing cells (APCs). However, the functional domain of Ov-ASP-1 as an adjuvant is not clearly defined. Based on...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Jingjing, Yang, Yi, Xiao, Wenjun, Sun, Weilai, Yu, Hong, Du, Lanying, Lustigman, Sara, Jiang, Shibo, Kou, Zhihua, Zhou, Yusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115538/
https://www.ncbi.nlm.nih.gov/pubmed/25736195
http://dx.doi.org/10.1016/j.vaccine.2015.02.053