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A truncated fragment of Ov-ASP-1 consisting of the core pathogenesis-related-1 (PR-1) domain maintains adjuvanticity as the full-length protein

The Onchocerca volvulus activation-associated secreted protein-1 (Ov-ASP-1) has good adjuvanticity for a variety of antigens and vaccines, probably due to its ability activate antigen-processing cells (APCs). However, the functional domain of Ov-ASP-1 as an adjuvant is not clearly defined. Based on...

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Detalles Bibliográficos
Autores principales:	Guo, Jingjing, Yang, Yi, Xiao, Wenjun, Sun, Weilai, Yu, Hong, Du, Lanying, Lustigman, Sara, Jiang, Shibo, Kou, Zhihua, Zhou, Yusen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115538/ https://www.ncbi.nlm.nih.gov/pubmed/25736195 http://dx.doi.org/10.1016/j.vaccine.2015.02.053

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