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Outer membrane vesicles harboring modified lipid A moiety augment the efficacy of an influenza vaccine exhibiting reduced endotoxicity in a mouse model

Influenza is an acute respiratory disease and a major health problem worldwide. Since mucosal immunity plays a critical role in protection against influenza virus infection, mucosal immunization is considered a promising vaccination route. However, except for live-attenuated vaccines, there are no e...

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Detalles Bibliográficos
Autores principales: Lee, Tae-Young, Kim, Chang-Ung, Bae, Eun-Hye, Seo, Sang-Hwan, Jeong, Dae Gwin, Yoon, Sun-Woo, Chang, Kyu-Tae, Kim, Young Sang, Kim, Sang-Hyun, Kim, Doo-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115551/
https://www.ncbi.nlm.nih.gov/pubmed/28024958
http://dx.doi.org/10.1016/j.vaccine.2016.12.025

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