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Cricket paralysis virus internal ribosome entry site-derived RNA promotes conventional vaccine efficacy by enhancing a balanced Th1/Th2 response

An ideal adjuvant should increase vaccine efficacy through balanced Th1/Th2 responses and be safe to use. Recombinant protein-based vaccines are usually formulated with aluminum (alum)-based adjuvants to ensure an adequate immune response. However, use of alum triggers a Th2-biased immune induction,...

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Detalles Bibliográficos
Autores principales:	Kwak, Hye Won, Park, Hyo-Jung, Ko, Hae Li, Park, Hyelim, Cha, Min Ho, Lee, Sang-Myeong, Kang, Kyung Won, Kim, Rhoon-Ho, Ryu, Seung Rok, Kim, Hye-Jung, Kim, Jae-Ouk, Song, Manki, Kim, Hun, Jeong, Dae Gwin, Shin, Eui-Cheol, Nam, Jae-Hwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115557/ https://www.ncbi.nlm.nih.gov/pubmed/31371226 http://dx.doi.org/10.1016/j.vaccine.2019.07.070

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