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Enhancement of immunostimulatory properties of exosomal vaccines by incorporation of fusion-competent G protein of vesicular stomatitis virus

Exosomes have been proposed as candidates for therapeutic immunization. The present study demonstrates that incorporation of the G protein of vesicular stomatitis virus (VSV-G) into exosome-like vesicles (ELVs) enhances their uptake and induces the maturation of dendritic cells. Targeting of VSV-G a...

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Detalles Bibliográficos
Autores principales: Temchura, Vladimir V., Tenbusch, Matthias, Nchinda, Godwin, Nabi, Ghulam, Tippler, Bettina, Zelenyuk, Maryna, Wildner, Oliver, Überla, Klaus, Kuate, Seraphin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115564/
https://www.ncbi.nlm.nih.gov/pubmed/18538453
http://dx.doi.org/10.1016/j.vaccine.2008.04.069