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SARS coronavirus spike polypeptide DNA vaccine priming with recombinant spike polypeptide from Escherichia coli as booster induces high titer of neutralizing antibody against SARS coronavirus

Different forms of SARS coronavirus (SARS-CoV) spike protein-based vaccines for generation of neutralizing antibody response against SARS-CoV were compared using a mouse model. High IgG levels were detected in mice immunized with intraperitoneal (i.p.) recombinant spike polypeptide generated by Esch...

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Detalles Bibliográficos
Autores principales:	Woo, Patrick C.Y., Lau, Susanna K.P., Tsoi, Hoi-wah, Chen, Zhi-wei, Wong, Beatrice H.L., Zhang, Linqi, Chan, Jim K.H., Wong, Lei-po, He, Wei, Ma, Chi, Chan, Kwok-hung, Ho, David D., Yuen, Kwok-yung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115571/ https://www.ncbi.nlm.nih.gov/pubmed/15993989 http://dx.doi.org/10.1016/j.vaccine.2005.05.023

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