Cargando…
Generation of predictive pharmacophore model for SARS-coronavirus main proteinase
Pharmacophore-based virtual screening is an effective, inexpensive and fast approach to discovering useful starting points for drug discovery. In this study, we developed a pharmacophore model for the main proteinase of severe acute respiratory syndrome coronavirus (SARS-CoV). Then we used this phar...
Autores principales: | Zhang, Xue Wu, Yap, Yee Leng, Altmeyer, Ralf M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier SAS.
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115589/ https://www.ncbi.nlm.nih.gov/pubmed/15642409 http://dx.doi.org/10.1016/j.ejmech.2004.09.013 |
Ejemplares similares
-
Exploring the binding mechanism of the main proteinase in SARS-associated coronavirus and its implication to anti-SARS drug design
por: Zhang, Xue Wu, et al.
Publicado: (2004) -
Old drugs as lead compounds for a new disease? Binding analysis of SARS coronavirus main proteinase with HIV, psychotic and parasite drugs
por: Zhang, Xue Wu, et al.
Publicado: (2004) -
Homology models of main proteinase from coronavirus associated with SARS
por: Liu, Hsuan-Liang, et al.
Publicado: (2005) -
Enzymatic activity of the SARS coronavirus main proteinase dimer
por: Graziano, Vito, et al.
Publicado: (2006) -
SARS coronavirus main proteinase 3.4.22.69
por: Schomburg, Dietmar, et al.
Publicado: (2013)