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Immunogenicity of a receptor-binding domain of SARS coronavirus spike protein in mice: Implications for a subunit vaccine

We studied the immunogenicity of an anti-SARS subunit vaccine comprised of the fragment of the SARS coronavirus (SARS-CoV) spike protein amino acids 318–510 (S318–510) containing the receptor-binding domain. The S protein fragment was purified from the culture supernatant of stably transformed HEK29...

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Detalles Bibliográficos
Autores principales: Zakhartchouk, Alexander N., Sharon, Chetna, Satkunarajah, Malathy, Auperin, Thierry, Viswanathan, Sathiyanarayanan, Mutwiri, George, Petric, Martin, See, Raymond H., Brunham, Robert C., Finlay, B. Brett, Cameron, Cheryl, Kelvin, David J., Cochrane, Alan, Rini, James M., Babiuk, Lorne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115608/
https://www.ncbi.nlm.nih.gov/pubmed/16919855
http://dx.doi.org/10.1016/j.vaccine.2006.06.084