Recombinant measles AIK-C vaccine strain expressing heterologous virus antigens

Further attenuated measles vaccines were developed more than 50 years ago and have been used throughout the world. Recombinant measles vaccine candidates have been developed and express several heterologous virus protective antigens. Immunogenicity and protective actions were confirmed using experim...

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Detalles Bibliográficos
Autores principales: Nakayama, Tetsuo, Sawada, Akihito, Yamaji, Yoshiaki, Ito, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115616/
https://www.ncbi.nlm.nih.gov/pubmed/26562316
http://dx.doi.org/10.1016/j.vaccine.2015.10.127
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author Nakayama, Tetsuo
Sawada, Akihito
Yamaji, Yoshiaki
Ito, Takashi
author_facet Nakayama, Tetsuo
Sawada, Akihito
Yamaji, Yoshiaki
Ito, Takashi
author_sort Nakayama, Tetsuo
collection PubMed
description Further attenuated measles vaccines were developed more than 50 years ago and have been used throughout the world. Recombinant measles vaccine candidates have been developed and express several heterologous virus protective antigens. Immunogenicity and protective actions were confirmed using experimental animals: transgenic mice, cotton rats, and primates. The recent development of measles vaccine-based vectored vaccine candidates has been reviewed and some information on recombinant measles vaccines expressing respiratory syncytial virus proteins has been shown and discussed.
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spelling pubmed-71156162020-04-02 Recombinant measles AIK-C vaccine strain expressing heterologous virus antigens Nakayama, Tetsuo Sawada, Akihito Yamaji, Yoshiaki Ito, Takashi Vaccine Article Further attenuated measles vaccines were developed more than 50 years ago and have been used throughout the world. Recombinant measles vaccine candidates have been developed and express several heterologous virus protective antigens. Immunogenicity and protective actions were confirmed using experimental animals: transgenic mice, cotton rats, and primates. The recent development of measles vaccine-based vectored vaccine candidates has been reviewed and some information on recombinant measles vaccines expressing respiratory syncytial virus proteins has been shown and discussed. Published by Elsevier Ltd. 2016-01-04 2015-11-10 /pmc/articles/PMC7115616/ /pubmed/26562316 http://dx.doi.org/10.1016/j.vaccine.2015.10.127 Text en Copyright © 2015 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Nakayama, Tetsuo
Sawada, Akihito
Yamaji, Yoshiaki
Ito, Takashi
Recombinant measles AIK-C vaccine strain expressing heterologous virus antigens
title Recombinant measles AIK-C vaccine strain expressing heterologous virus antigens
title_full Recombinant measles AIK-C vaccine strain expressing heterologous virus antigens
title_fullStr Recombinant measles AIK-C vaccine strain expressing heterologous virus antigens
title_full_unstemmed Recombinant measles AIK-C vaccine strain expressing heterologous virus antigens
title_short Recombinant measles AIK-C vaccine strain expressing heterologous virus antigens
title_sort recombinant measles aik-c vaccine strain expressing heterologous virus antigens
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115616/
https://www.ncbi.nlm.nih.gov/pubmed/26562316
http://dx.doi.org/10.1016/j.vaccine.2015.10.127
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AT itotakashi recombinantmeaslesaikcvaccinestrainexpressingheterologousvirusantigens

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