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Novel NSAID 1-acyl-4-cycloalkyl/arylsemicarbazides and 1-acyl-5-benzyloxy/hydroxy carbamoylcarbazides as potential anticancer agents and antioxidants

The novel 1-acyl-4-cycloalkyl/arylsemicarbazides (5a–y) and 1-acyl-5-benzyloxy/hydroxycarbamoylcarbazides (8a–f) derived from the nonsteroidal anti-inflammatory drugs ibuprofen, fenoprofen and reduced ketoprofen were prepared, fully chemically characterized and evaluated for their cytostatic, antivi...

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Detalles Bibliográficos
Autores principales: Perković, I., Butula, I., Kralj, M., Martin-Kleiner, I., Balzarini, J., Hadjipavlou-Litina, D., Katsori, A.-M., Zorc, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115626/
https://www.ncbi.nlm.nih.gov/pubmed/22405290
http://dx.doi.org/10.1016/j.ejmech.2012.02.046