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Vaccination of calves using the BRSV nucleocapsid protein in a DNA prime–protein boost strategy stimulates cell-mediated immunity and protects the lungs against BRSV replication and pathology

Respiratory syncytial virus (RSV) is a major cause of respiratory disease in both cattle and young children. Despite the development of vaccines against bovine (B)RSV, incomplete protection and exacerbation of subsequent RSV disease have occurred. In order to circumvent these problems, calves were v...

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Detalles Bibliográficos
Autores principales: Carine, Letellier, Mathieu, Boxus, Laurent, Rosar, Jean-François, Toussaint, Karl, Walravens, Stefan, Roels, Gilles, Meyer, Jean-Jacques, Letesson, Pierre, Kerkhofs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115630/
https://www.ncbi.nlm.nih.gov/pubmed/18644416
http://dx.doi.org/10.1016/j.vaccine.2008.06.100