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An inactivated West Nile Virus vaccine derived from a chemically synthesized cDNA system

A cDNA comprising the complete genome of West Nile Virus (WNV) was generated by chemical synthesis using published sequence data, independent of any preformed viral components. The synthetic WNV, produced by transfection of in vitro transcribed RNA into cell culture, exhibited undistinguishable biol...

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Detalles Bibliográficos
Autores principales: Orlinger, Klaus K., Holzer, Georg W., Schwaiger, Julia, Mayrhofer, Josef, Schmid, Karl, Kistner, Otfried, Noel Barrett, P., Falkner, Falko G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115638/
https://www.ncbi.nlm.nih.gov/pubmed/20211218
http://dx.doi.org/10.1016/j.vaccine.2010.02.092