Cargando…

Synthesis and affinity to DNA of phenylbenzoimidazoles and benzoimidazo[1,2-c]quinazolines

Novel N-(benzoimidazophenyl)dialkylaminoalkylamides and 6-dialkylaminoalkylbenzoimidazo[1,2-c]quinazolines were prepared as potential interferon inducers and antiviral agents. They were screened for the DNA affinity by the ethidium bromide displacement assay. It was shown that the lg K(a) values of ...

Descripción completa

Detalles Bibliográficos
Autores principales: Lyakhova, Elena A., Gusyeva, Yulia A., Nekhoroshkova, Julia V., Shafran, Lev M., Lyakhov, Sergey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115644/
https://www.ncbi.nlm.nih.gov/pubmed/19349097
http://dx.doi.org/10.1016/j.ejmech.2009.03.004