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Synthesis and structure-activity relationship studies of water-soluble β-cyclodextrin-glycyrrhetinic acid conjugates as potential anti-influenza virus agents

Glycyrrhetinic acid (GA) is a major constituent of the herb Glycyrrhiza glabra, and many of its derivatives demonstrate a broad spectrum of antiviral activities. In the current study, 18 water-soluble β-cyclodextrin (CD)-GA conjugates, in which GA was covalently coupled to the primary face of β-CD u...

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Detalles Bibliográficos
Autores principales: Liang, Shuobin, Li, Man, Yu, Xiaojuan, Jin, Hongwei, Zhang, Yongmin, Zhang, Lihe, Zhou, Demin, Xiao, Sulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115653/
https://www.ncbi.nlm.nih.gov/pubmed/30731401
http://dx.doi.org/10.1016/j.ejmech.2019.01.074