Synthetic peptides coupled to the surface of liposomes effectively induce SARS coronavirus-specific cytotoxic T lymphocytes and viral clearance in HLA-A*0201 transgenic mice

We investigated whether the surface-linked liposomal peptide was applicable to a vaccine based on cytotoxic T lymphocytes (CTLs) against severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV). We first identified four HLA-A*0201-restricted CTL epitopes derived from SARS-CoV using HLA-A*0201...

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Detalles Bibliográficos
Autores principales: Ohno, Satoshi, Kohyama, Shunsuke, Taneichi, Maiko, Moriya, Osamu, Hayashi, Hidenori, Oda, Hiroshi, Mori, Masahito, Kobayashi, Akiharu, Akatsuka, Toshitaka, Uchida, Tetsuya, Matsui, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115666/
https://www.ncbi.nlm.nih.gov/pubmed/19490987
http://dx.doi.org/10.1016/j.vaccine.2009.04.001

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