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Manifestaciones neuroftalmológicas como complicación de una infección por Mycoplasma pneumoniae y desarrollo posterior de una encefalitis aguda diseminada

The purpose of this article is to describe two paediatric neuro-ophthalmological clinical cases caused by a systemic infection due to Mycoplasma pneumoniae (M. pneumoniae). The cases are two girls aged 14 and 12 seen in the Emergency Department: The first one had internuclear ophthalmoplegia and sec...

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Autores principales: Molero-Senosiain, M., Domingo-Gordo, B., Fernández Cabrera, C., Hernández-García, E., Gómez de Liaño, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115784/
https://www.ncbi.nlm.nih.gov/pubmed/32147128
http://dx.doi.org/10.1016/j.oftal.2020.01.009
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author Molero-Senosiain, M.
Domingo-Gordo, B.
Fernández Cabrera, C.
Hernández-García, E.
Gómez de Liaño, R.
author_facet Molero-Senosiain, M.
Domingo-Gordo, B.
Fernández Cabrera, C.
Hernández-García, E.
Gómez de Liaño, R.
author_sort Molero-Senosiain, M.
collection PubMed
description The purpose of this article is to describe two paediatric neuro-ophthalmological clinical cases caused by a systemic infection due to Mycoplasma pneumoniae (M. pneumoniae). The cases are two girls aged 14 and 12 seen in the Emergency Department: The first one had internuclear ophthalmoplegia and second with loss of vision and headache. They had no other neurological foci. Magnetic resonance imaging showed hyperintense plaques in both, suggestive of a demyelinating disease. One month later, the neuro-ophthalmological symptoms resolved, with normal follow-up magnetic resonance imagings. The diagnosis was acute disseminated encephalitis secondary to M. pneumoniae. The diagnosis was made using PCR (gold standard) and/or IgM in serology. It is important to think about this possible aetiology in cases of suggestive demyelinating disease. There is controversy about the role of antibiotics and on whether corticosteroids are contemplated. In conclusion, M. pneumoniae must be a differential diagnosis in acute neuro-ophthalmological disorders in children.
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spelling pubmed-71157842020-04-02 Manifestaciones neuroftalmológicas como complicación de una infección por Mycoplasma pneumoniae y desarrollo posterior de una encefalitis aguda diseminada Molero-Senosiain, M. Domingo-Gordo, B. Fernández Cabrera, C. Hernández-García, E. Gómez de Liaño, R. Arch Soc Esp Oftalmol Article The purpose of this article is to describe two paediatric neuro-ophthalmological clinical cases caused by a systemic infection due to Mycoplasma pneumoniae (M. pneumoniae). The cases are two girls aged 14 and 12 seen in the Emergency Department: The first one had internuclear ophthalmoplegia and second with loss of vision and headache. They had no other neurological foci. Magnetic resonance imaging showed hyperintense plaques in both, suggestive of a demyelinating disease. One month later, the neuro-ophthalmological symptoms resolved, with normal follow-up magnetic resonance imagings. The diagnosis was acute disseminated encephalitis secondary to M. pneumoniae. The diagnosis was made using PCR (gold standard) and/or IgM in serology. It is important to think about this possible aetiology in cases of suggestive demyelinating disease. There is controversy about the role of antibiotics and on whether corticosteroids are contemplated. In conclusion, M. pneumoniae must be a differential diagnosis in acute neuro-ophthalmological disorders in children. Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. 2020-05 2020-03-05 /pmc/articles/PMC7115784/ /pubmed/32147128 http://dx.doi.org/10.1016/j.oftal.2020.01.009 Text en © 2020 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Molero-Senosiain, M.
Domingo-Gordo, B.
Fernández Cabrera, C.
Hernández-García, E.
Gómez de Liaño, R.
Manifestaciones neuroftalmológicas como complicación de una infección por Mycoplasma pneumoniae y desarrollo posterior de una encefalitis aguda diseminada
title Manifestaciones neuroftalmológicas como complicación de una infección por Mycoplasma pneumoniae y desarrollo posterior de una encefalitis aguda diseminada
title_full Manifestaciones neuroftalmológicas como complicación de una infección por Mycoplasma pneumoniae y desarrollo posterior de una encefalitis aguda diseminada
title_fullStr Manifestaciones neuroftalmológicas como complicación de una infección por Mycoplasma pneumoniae y desarrollo posterior de una encefalitis aguda diseminada
title_full_unstemmed Manifestaciones neuroftalmológicas como complicación de una infección por Mycoplasma pneumoniae y desarrollo posterior de una encefalitis aguda diseminada
title_short Manifestaciones neuroftalmológicas como complicación de una infección por Mycoplasma pneumoniae y desarrollo posterior de una encefalitis aguda diseminada
title_sort manifestaciones neuroftalmológicas como complicación de una infección por mycoplasma pneumoniae y desarrollo posterior de una encefalitis aguda diseminada
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115784/
https://www.ncbi.nlm.nih.gov/pubmed/32147128
http://dx.doi.org/10.1016/j.oftal.2020.01.009
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