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Bridging the Gaps: Bole and Terra Sigillata as Artefacts, as Simples and as Antibacterial Clays

Medicinal earths are an important and yet, so far, little scientifically explored archaeological resource. They are almost always identified by their source locality. Our work over the last few years has focused on their chemical and mineralogical characterization and their testing as anti-bacterial...

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Autores principales: Venieri, Danae, Gounaki, Iosifina, Christidis, George E., Knapp, Charles W., Bouras-Vallianatos, Petros, Photos-Jones, Effie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115821/
https://www.ncbi.nlm.nih.gov/pubmed/32724664
http://dx.doi.org/10.3390/min10040348
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author Venieri, Danae
Gounaki, Iosifina
Christidis, George E.
Knapp, Charles W.
Bouras-Vallianatos, Petros
Photos-Jones, Effie
author_facet Venieri, Danae
Gounaki, Iosifina
Christidis, George E.
Knapp, Charles W.
Bouras-Vallianatos, Petros
Photos-Jones, Effie
author_sort Venieri, Danae
collection PubMed
description Medicinal earths are an important and yet, so far, little scientifically explored archaeological resource. They are almost always identified by their source locality. Our work over the last few years has focused on their chemical and mineralogical characterization and their testing as anti-bacterials. This paper presents the results of the mineralogical analysis and antibacterial testing of six medicinal earths, bole or Terra Sigillata (stamped earth) of unknown date and provenance in the Pharmacy Museum of the University of Basel. Only one of them, a red (Armenian?) ‘bole’, was found to be antibacterial against both Gram-positive and Gram-negative bacteria. A yellow powder of Terra Tripolitania was mildly antibacterial and against one pathogen only. We argue that medicinal earths are in a pivotal place to bridge the gap between currently dispersed pieces of information. This information relates to: (a) their nature, attributes, and applications as described in the texts of different periods, (b) the source of their clays and how best to locate them in the field today, and (c) the methods employed for their beneficiation, if known. We propose that work should be focused primarily onto those medicinal earths whose clay sources can be re-discovered, sampled and assessed. From then on, a parallel investigation should be initiated involving both earths and their natural clays (mineralogy at bulk and nano-sized levels, bio-geochemistry, microbiological testing). We argue that the combined study can shed light into the parameters driving antibacterial action in clays and assist in the elucidation of the mechanisms involved.
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spelling pubmed-71158212020-07-28 Bridging the Gaps: Bole and Terra Sigillata as Artefacts, as Simples and as Antibacterial Clays Venieri, Danae Gounaki, Iosifina Christidis, George E. Knapp, Charles W. Bouras-Vallianatos, Petros Photos-Jones, Effie Minerals (Basel) Article Medicinal earths are an important and yet, so far, little scientifically explored archaeological resource. They are almost always identified by their source locality. Our work over the last few years has focused on their chemical and mineralogical characterization and their testing as anti-bacterials. This paper presents the results of the mineralogical analysis and antibacterial testing of six medicinal earths, bole or Terra Sigillata (stamped earth) of unknown date and provenance in the Pharmacy Museum of the University of Basel. Only one of them, a red (Armenian?) ‘bole’, was found to be antibacterial against both Gram-positive and Gram-negative bacteria. A yellow powder of Terra Tripolitania was mildly antibacterial and against one pathogen only. We argue that medicinal earths are in a pivotal place to bridge the gap between currently dispersed pieces of information. This information relates to: (a) their nature, attributes, and applications as described in the texts of different periods, (b) the source of their clays and how best to locate them in the field today, and (c) the methods employed for their beneficiation, if known. We propose that work should be focused primarily onto those medicinal earths whose clay sources can be re-discovered, sampled and assessed. From then on, a parallel investigation should be initiated involving both earths and their natural clays (mineralogy at bulk and nano-sized levels, bio-geochemistry, microbiological testing). We argue that the combined study can shed light into the parameters driving antibacterial action in clays and assist in the elucidation of the mechanisms involved. 2020-04-14 /pmc/articles/PMC7115821/ /pubmed/32724664 http://dx.doi.org/10.3390/min10040348 Text en http://creativecommons.org/licenses/by/4.0/ Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Venieri, Danae
Gounaki, Iosifina
Christidis, George E.
Knapp, Charles W.
Bouras-Vallianatos, Petros
Photos-Jones, Effie
Bridging the Gaps: Bole and Terra Sigillata as Artefacts, as Simples and as Antibacterial Clays
title Bridging the Gaps: Bole and Terra Sigillata as Artefacts, as Simples and as Antibacterial Clays
title_full Bridging the Gaps: Bole and Terra Sigillata as Artefacts, as Simples and as Antibacterial Clays
title_fullStr Bridging the Gaps: Bole and Terra Sigillata as Artefacts, as Simples and as Antibacterial Clays
title_full_unstemmed Bridging the Gaps: Bole and Terra Sigillata as Artefacts, as Simples and as Antibacterial Clays
title_short Bridging the Gaps: Bole and Terra Sigillata as Artefacts, as Simples and as Antibacterial Clays
title_sort bridging the gaps: bole and terra sigillata as artefacts, as simples and as antibacterial clays
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115821/
https://www.ncbi.nlm.nih.gov/pubmed/32724664
http://dx.doi.org/10.3390/min10040348
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