Highly rearranged chromosomes reveal uncoupling between genome topology and gene expression

Chromatin topology is intricately linked to gene expression, yet its functional requirement remains unclear. Here, we comprehensively assessed the interplay between genome topology and gene expression using highly rearranged chromosomes (balancers) spanning ~75% of the Drosophila genome. Using trans...

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Detalles Bibliográficos
Autores principales: Ghavi-Helm, Yad, Jankowski, Aleksander, Meiers, Sascha, Viales, Rebecca R., Korbel, Jan O., Furlong, Eileen E.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116017/
https://www.ncbi.nlm.nih.gov/pubmed/31308546
http://dx.doi.org/10.1038/s41588-019-0462-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116017/
https://www.ncbi.nlm.nih.gov/pubmed/31308546
http://dx.doi.org/10.1038/s41588-019-0462-3

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