Cargando…
Highly rearranged chromosomes reveal uncoupling between genome topology and gene expression
Chromatin topology is intricately linked to gene expression, yet its functional requirement remains unclear. Here, we comprehensively assessed the interplay between genome topology and gene expression using highly rearranged chromosomes (balancers) spanning ~75% of the Drosophila genome. Using trans...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116017/ https://www.ncbi.nlm.nih.gov/pubmed/31308546 http://dx.doi.org/10.1038/s41588-019-0462-3 |