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The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism

IκB kinase ε (IKKε) is a key molecule at the crossroads of inflammation and cancer. Known to regulate cytokine secretion via NFκB and IRF3, the kinase is also a breast cancer oncogene, overexpressed in a variety of tumours. However, to what extent IKKε remodels cellular metabolism is currently unkno...

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Detalles Bibliográficos
Autores principales:	Xu, Ruoyan, Jones, William, Wilcz‐Villega, Ewa, Costa, Ana SH, Rajeeve, Vinothini, Bentham, Robert B, Bryson, Kevin, Nagano, Ai, Yaman, Busra, Olendo Barasa, Sheila, Wang, Yewei, Chelala, Claude, Cutillas, Pedro, Szabadkai, Gyorgy, Frezza, Christian, Bianchi, Katiuscia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116048/ https://www.ncbi.nlm.nih.gov/pubmed/32783398 http://dx.doi.org/10.15252/embr.201948260

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