The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function

Genome-wide association studies (GWAS) of psychiatric phenotypes have tended to focus on categorical diagnoses, but to understand the biology of mental illness it may be more useful to study traits which cut across traditional boundaries. Here we report the results of a GWAS of mood instability as a...

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Detalles Bibliográficos
Autores principales: Ward, Joey, Tunbridge, Elizabeth M., Sandor, Cynthia, Lyall, Laura M., Ferguson, Amy, Strawbridge, Rona J., Lyall, Donald M., Cullen, Breda, Graham, Nicholas, Johnston, Keira J.A., Webber, Caleb, Escott-Price, Valentina, O’Donovan, Michael, Pell, Jill P., Bailey, Mark E.S., Harrison, Paul J., Smith, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116257/
https://www.ncbi.nlm.nih.gov/pubmed/31168069
http://dx.doi.org/10.1038/s41380-019-0439-8

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