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Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score

OBJECTIVE: To develop and validate a pragmatic risk score to predict mortality in patients admitted to hospital with coronavirus disease 2019 (covid-19). DESIGN: Prospective observational cohort study. SETTING: International Severe Acute Respiratory and emerging Infections Consortium (ISARIC) World...

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Autores principales: Knight, Stephen R, Ho, Antonia, Pius, Riinu, Buchan, Iain, Carson, Gail, Drake, Thomas M, Dunning, Jake, Fairfield, Cameron J, Gamble, Carrol, Green, Christopher A, Gupta, Rishi, Halpin, Sophie, Hardwick, Hayley E, Holden, Karl A, Horby, Peter W, Jackson, Clare, Mclean, Kenneth A, Merson, Laura, Nguyen-Van-Tam, Jonathan S, Norman, Lisa, Noursadeghi, Mahdad, Olliaro, Piero L, Pritchard, Mark G, Russell, Clark D, Shaw, Catherine A, Sheikh, Aziz, Solomon, Tom, Sudlow, Cathie, Swann, Olivia V, Turtle, Lance CW, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G, Docherty, Annemarie B, Harrison, Ewen M, Alex, Beatrice, Bach, Benjamin, Barclay, Wendy S, Bogaert, Debby, Chand, Meera, Cooke, Graham S, da Silva Filipe, Ana, Fletcher, Tom, Hiscox, Julian A, Ho, Antonia Ying Wai, Ijaz, Samreen, Khoo, Saye, Klenerman, Paul, Law, Andrew, Lim, Wei Shen, Mentzer, Alexander J, Meynert, Alison M, Moore, Shona C, Palmarini, Massimo, Paxton, William A, Pollakis, Georgios, Price, Nicholas, Rambaut, Andrew, Robertson, David L, Sancho-Shimizu, Vanessa, Scott, Janet T, Sigfrid, Louise, Sriskandan, Shiranee, Stuart, David, Summers, Charlotte, Tedder, Richard S, Thomson, Emma C, Thwaites, Ryan S, Zambon, Maria, Hardwick, Hayley, Donohue, Chloe, Ewins, Jane, Oosthuyzen, Wilna, Griffiths, Fiona, Drake, Tom M, Knight, Stephen, Murphy, Derek, Dalton, Jo, Girvan, Michelle, Saviciute, Egle, Roberts, Stephanie, Harrison, Janet, Marsh, Laura, Connor, Marie, Leeming, Gary, Hendry, Ross, Scott-Brown, James, Greenhalf, William, Shaw, Victoria, McDonald, Sarah, Ahmed, Katie A, Armstrong, Jane A, Ashworth, Milton, Asiimwe, Innocent G, Bakshi, Siddharth, Barlow, Samantha L, Booth, Laura, Brennan, Benjamin, Bullock, Katie, Catterall, Benjamin WA, Clark, Jordan J, Clarke, Emily A, Cole, Sarah, Cooper, Louise, Cox, Helen, Davis, Christopher, Dincarslan, Oslem, Dunn, Chris, Dyer, Philip, Elliott, Angela, Evans, Anthony, Fisher, Lewis WS, Foster, Terry, Garcia-Dorival, Isabel, Greenhalf, Willliam, Gunning, Philip, Hartley, Catherine, Jensen, Rebecca L, Jones, Christopher B, Jones, Trevor R, Khandaker, Shadia, King, Katharine, Kiy, Robyn T, Koukorava, Chrysa, Lake, Annette, Lant, Suzannah, Latawiec, Diane, Lavelle-Langham, L, Lefteri, Daniella, Lett, Lauren, Livoti, Lucia A, Mancini, Maria, McEvoy, Laurence, McLauchlan, John, Metelmann, Soeren, Miah, Nahida S, Middleton, Joanna, Mitchell, Joyce, Murphy, Ellen G, Penrice-Randal, Rebekah, Pilgrim, Jack, Prince, Tessa, Reynolds, Will, Ridley, P Matthew, Sales, Debby, Shaw, Victoria E, Shears, Rebecca K, Small, Benjamin, Subramaniam, Krishanthi S, Szemiel, Agnieska, Taggart, Aislynn, Tanianis-Hughes, Jolanta, Thomas, Jordan, Trochu, Erwan, van Tonder, Libby, Wilcock, Eve, Zhang, J Eunice, Adeniji, Kayode, Agranoff, Daniel, Agwuh, Ken, Ail, Dhiraj, Alegria, Ana, Angus, Brian, Ashish, Abdul, Atkinson, Dougal, Bari, Shahedal, Barlow, Gavin, Barnass, Stella, Barrett, Nicholas, Bassford, Christopher, Baxter, David, Beadsworth, Michael, Bernatoniene, Jolanta, Berridge, John, Best, Nicola, Bothma, Pieter, Brealey, David, Brittain-Long, Robin, Bulteel, Naomi, Burden, Tom, Burtenshaw, Andrew, Caruth, Vikki, Chadwick, David, Chambler, Duncan, Chee, Nigel, Child, Jenny, Chukkambotla, Srikanth, Clark, Tom, Collini, Paul, Cosgrove, Catherine, Cupitt, Jason, Cutino-Moguel, Maria-Teresa, Dark, Paul, Dawson, Chris, Dervisevic, Samir, Donnison, Phil, Douthwaite, Sam, DuRand, Ingrid, Dushianthan, Ahilanadan, Dyer, Tristan, Evans, Cariad, Eziefula, Chi, Fegan, Chrisopher, Finn, Adam, Fullerton, Duncan, Garg, Sanjeev, Garg, Atul, Godden, Jo, Goldsmith, Arthur, Graham, Clive, Hardy, Elaine, Hartshorn, Stuart, Harvey, Daniel, Havalda, Peter, Hawcutt, Daniel B, Hobrok, Maria, Hodgson, Luke, Holme, Anita, Hormis, Anil, Jacobs, Michael, Jain, Susan, Jennings, Paul, Kaliappan, Agilan, Kasipandian, Vidya, Kegg, Stephen, Kelsey, Michael, Kendall, Jason, Kerrison, Caroline, Kerslake, Ian, Koch, Oliver, Koduri, Gouri, Koshy, George, Laha, Shondipon, Larkin, Susan, Leiner, Tamas, Lillie, Patrick, Limb, James, Linnett, Vanessa, Little, Jeff, MacMahon, Michael, MacNaughton, Emily, Mankregod, Ravish, Masson, Huw, Matovu, Elijah, McCullough, Katherine, McEwen, Ruth, Meda, Manjula, Mills, Gary, Minton, Jane, Mirfenderesky, Mariyam, Mohandas, Kavya, Mok, Quen, Moon, James, Moore, Elinoor, Morgan, Patrick, Morris, Craig, Mortimore, Katherine, Moses, Samuel, Mpenge, Mbiye, Mulla, Rohinton, Murphy, Michael, Nagel, Megan, Nagarajan, Thapas, Nelson, Mark, Otahal, Igor, Pais, Mark, Panchatsharam, Selva, Paraiso, Hassan, Patel, Brij, Pepperell, Justin, Peters, Mark, Phull, Mandeep, Pintus, Stefania, Pooni, Jagtur Singh, Post, Frank, Price, David, Prout, Rachel, Rae, Nikolas, Reschreiter, Henrik, Reynolds, Tim, Richardson, Neil, Roberts, Mark, Roberts, Devender, Rose, Alistair, Rousseau, Guy, Ryan, Brendan, Saluja, Taranprit, Shah, Aarti, Shanmuga, Prad, Sharma, Anil, Shawcross, Anna, Sizer, Jeremy, Smith, Richard, Snelson, Catherine, Spittle, Nick, Staines, Nikki, Stambach, Tom, Stewart, Richard, Subudhi, Pradeep, Szakmany, Tamas, Tatham, Kate, Thomas, Jo, Thompson, Chris, Thompson, Robert, Tridente, Ascanio, Tupper-Carey, Darell, Twagira, Mary, Ustianowski, Andrew, Vallotton, Nick, Vincent-Smith, Lisa, Visuvanathan, Shico, Vuylsteke, Alan, Waddy, Sam, Wake, Rachel, Walden, Andrew, Welters, Ingeborg, Whitehouse, Tony, Whittaker, Paul, Whittington, Ashley, Wijesinghe, Meme, Williams, Martin, Wilson, Lawrence, Wilson, Sarah, Winchester, Stephen, Wiselka, Martin, Wolverson, Adam, Wooton, Daniel G, Workman, Andrew, Yates, Bryan, Young, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116472/
https://www.ncbi.nlm.nih.gov/pubmed/32907855
http://dx.doi.org/10.1136/bmj.m3339
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author Knight, Stephen R
Ho, Antonia
Pius, Riinu
Buchan, Iain
Carson, Gail
Drake, Thomas M
Dunning, Jake
Fairfield, Cameron J
Gamble, Carrol
Green, Christopher A
Gupta, Rishi
Halpin, Sophie
Hardwick, Hayley E
Holden, Karl A
Horby, Peter W
Jackson, Clare
Mclean, Kenneth A
Merson, Laura
Nguyen-Van-Tam, Jonathan S
Norman, Lisa
Noursadeghi, Mahdad
Olliaro, Piero L
Pritchard, Mark G
Russell, Clark D
Shaw, Catherine A
Sheikh, Aziz
Solomon, Tom
Sudlow, Cathie
Swann, Olivia V
Turtle, Lance CW
Openshaw, Peter JM
Baillie, J Kenneth
Semple, Malcolm G
Docherty, Annemarie B
Harrison, Ewen M
Baillie, J Kenneth
Semple, Malcolm G
Openshaw, Peter JM
Carson, Gail
Alex, Beatrice
Bach, Benjamin
Barclay, Wendy S
Bogaert, Debby
Chand, Meera
Cooke, Graham S
Docherty, Annemarie B
Dunning, Jake
da Silva Filipe, Ana
Fletcher, Tom
Green, Christopher A
Harrison, Ewen M
Hiscox, Julian A
Ho, Antonia Ying Wai
Horby, Peter W
Ijaz, Samreen
Khoo, Saye
Klenerman, Paul
Law, Andrew
Lim, Wei Shen
Mentzer, Alexander J
Merson, Laura
Meynert, Alison M
Noursadeghi, Mahdad
Moore, Shona C
Palmarini, Massimo
Paxton, William A
Pollakis, Georgios
Price, Nicholas
Rambaut, Andrew
Robertson, David L
Russell, Clark D
Sancho-Shimizu, Vanessa
Scott, Janet T
Sigfrid, Louise
Solomon, Tom
Sriskandan, Shiranee
Stuart, David
Summers, Charlotte
Tedder, Richard S
Thomson, Emma C
Thwaites, Ryan S
Turtle, Lance CW
Zambon, Maria
Hardwick, Hayley
Donohue, Chloe
Ewins, Jane
Oosthuyzen, Wilna
Griffiths, Fiona
Norman, Lisa
Pius, Riinu
Drake, Tom M
Fairfield, Cameron J
Knight, Stephen
Mclean, Kenneth A
Murphy, Derek
Shaw, Catherine A
Dalton, Jo
Girvan, Michelle
Saviciute, Egle
Roberts, Stephanie
Harrison, Janet
Marsh, Laura
Connor, Marie
Halpin, Sophie
Jackson, Clare
Gamble, Carrol
Leeming, Gary
Law, Andrew
Hendry, Ross
Scott-Brown, James
Greenhalf, William
Shaw, Victoria
McDonald, Sarah
Ahmed, Katie A
Armstrong, Jane A
Ashworth, Milton
Asiimwe, Innocent G
Bakshi, Siddharth
Barlow, Samantha L
Booth, Laura
Brennan, Benjamin
Bullock, Katie
Catterall, Benjamin WA
Clark, Jordan J
Clarke, Emily A
Cole, Sarah
Cooper, Louise
Cox, Helen
Davis, Christopher
Dincarslan, Oslem
Dunn, Chris
Dyer, Philip
Elliott, Angela
Evans, Anthony
Fisher, Lewis WS
Foster, Terry
Garcia-Dorival, Isabel
Greenhalf, Willliam
Gunning, Philip
Hartley, Catherine
Ho, Antonia
Jensen, Rebecca L
Jones, Christopher B
Jones, Trevor R
Khandaker, Shadia
King, Katharine
Kiy, Robyn T
Koukorava, Chrysa
Lake, Annette
Lant, Suzannah
Latawiec, Diane
Lavelle-Langham, L
Lefteri, Daniella
Lett, Lauren
Livoti, Lucia A
Mancini, Maria
McDonald, Sarah
McEvoy, Laurence
McLauchlan, John
Metelmann, Soeren
Miah, Nahida S
Middleton, Joanna
Mitchell, Joyce
Moore, Shona C
Murphy, Ellen G
Penrice-Randal, Rebekah
Pilgrim, Jack
Prince, Tessa
Reynolds, Will
Ridley, P Matthew
Sales, Debby
Shaw, Victoria E
Shears, Rebecca K
Small, Benjamin
Subramaniam, Krishanthi S
Szemiel, Agnieska
Taggart, Aislynn
Tanianis-Hughes, Jolanta
Thomas, Jordan
Trochu, Erwan
van Tonder, Libby
Wilcock, Eve
Zhang, J Eunice
Adeniji, Kayode
Agranoff, Daniel
Agwuh, Ken
Ail, Dhiraj
Alegria, Ana
Angus, Brian
Ashish, Abdul
Atkinson, Dougal
Bari, Shahedal
Barlow, Gavin
Barnass, Stella
Barrett, Nicholas
Bassford, Christopher
Baxter, David
Beadsworth, Michael
Bernatoniene, Jolanta
Berridge, John
Best, Nicola
Bothma, Pieter
Brealey, David
Brittain-Long, Robin
Bulteel, Naomi
Burden, Tom
Burtenshaw, Andrew
Caruth, Vikki
Chadwick, David
Chambler, Duncan
Chee, Nigel
Child, Jenny
Chukkambotla, Srikanth
Clark, Tom
Collini, Paul
Cosgrove, Catherine
Cupitt, Jason
Cutino-Moguel, Maria-Teresa
Dark, Paul
Dawson, Chris
Dervisevic, Samir
Donnison, Phil
Douthwaite, Sam
DuRand, Ingrid
Dushianthan, Ahilanadan
Dyer, Tristan
Evans, Cariad
Eziefula, Chi
Fegan, Chrisopher
Finn, Adam
Fullerton, Duncan
Garg, Sanjeev
Garg, Sanjeev
Garg, Atul
Godden, Jo
Goldsmith, Arthur
Graham, Clive
Hardy, Elaine
Hartshorn, Stuart
Harvey, Daniel
Havalda, Peter
Hawcutt, Daniel B
Hobrok, Maria
Hodgson, Luke
Holme, Anita
Hormis, Anil
Jacobs, Michael
Jain, Susan
Jennings, Paul
Kaliappan, Agilan
Kasipandian, Vidya
Kegg, Stephen
Kelsey, Michael
Kendall, Jason
Kerrison, Caroline
Kerslake, Ian
Koch, Oliver
Koduri, Gouri
Koshy, George
Laha, Shondipon
Larkin, Susan
Leiner, Tamas
Lillie, Patrick
Limb, James
Linnett, Vanessa
Little, Jeff
MacMahon, Michael
MacNaughton, Emily
Mankregod, Ravish
Masson, Huw
Matovu, Elijah
McCullough, Katherine
McEwen, Ruth
Meda, Manjula
Mills, Gary
Minton, Jane
Mirfenderesky, Mariyam
Mohandas, Kavya
Mok, Quen
Moon, James
Moore, Elinoor
Morgan, Patrick
Morris, Craig
Mortimore, Katherine
Moses, Samuel
Mpenge, Mbiye
Mulla, Rohinton
Murphy, Michael
Nagel, Megan
Nagarajan, Thapas
Nelson, Mark
Otahal, Igor
Pais, Mark
Panchatsharam, Selva
Paraiso, Hassan
Patel, Brij
Pepperell, Justin
Peters, Mark
Phull, Mandeep
Pintus, Stefania
Pooni, Jagtur Singh
Post, Frank
Price, David
Prout, Rachel
Rae, Nikolas
Reschreiter, Henrik
Reynolds, Tim
Richardson, Neil
Roberts, Mark
Roberts, Devender
Rose, Alistair
Rousseau, Guy
Ryan, Brendan
Saluja, Taranprit
Shah, Aarti
Shanmuga, Prad
Sharma, Anil
Shawcross, Anna
Sizer, Jeremy
Smith, Richard
Snelson, Catherine
Spittle, Nick
Staines, Nikki
Stambach, Tom
Stewart, Richard
Subudhi, Pradeep
Szakmany, Tamas
Tatham, Kate
Thomas, Jo
Thompson, Chris
Thompson, Robert
Tridente, Ascanio
Tupper-Carey, Darell
Twagira, Mary
Ustianowski, Andrew
Vallotton, Nick
Vincent-Smith, Lisa
Visuvanathan, Shico
Vuylsteke, Alan
Waddy, Sam
Wake, Rachel
Walden, Andrew
Welters, Ingeborg
Whitehouse, Tony
Whittaker, Paul
Whittington, Ashley
Wijesinghe, Meme
Williams, Martin
Wilson, Lawrence
Wilson, Sarah
Winchester, Stephen
Wiselka, Martin
Wolverson, Adam
Wooton, Daniel G
Workman, Andrew
Yates, Bryan
Young, Peter
author_facet Knight, Stephen R
Ho, Antonia
Pius, Riinu
Buchan, Iain
Carson, Gail
Drake, Thomas M
Dunning, Jake
Fairfield, Cameron J
Gamble, Carrol
Green, Christopher A
Gupta, Rishi
Halpin, Sophie
Hardwick, Hayley E
Holden, Karl A
Horby, Peter W
Jackson, Clare
Mclean, Kenneth A
Merson, Laura
Nguyen-Van-Tam, Jonathan S
Norman, Lisa
Noursadeghi, Mahdad
Olliaro, Piero L
Pritchard, Mark G
Russell, Clark D
Shaw, Catherine A
Sheikh, Aziz
Solomon, Tom
Sudlow, Cathie
Swann, Olivia V
Turtle, Lance CW
Openshaw, Peter JM
Baillie, J Kenneth
Semple, Malcolm G
Docherty, Annemarie B
Harrison, Ewen M
Baillie, J Kenneth
Semple, Malcolm G
Openshaw, Peter JM
Carson, Gail
Alex, Beatrice
Bach, Benjamin
Barclay, Wendy S
Bogaert, Debby
Chand, Meera
Cooke, Graham S
Docherty, Annemarie B
Dunning, Jake
da Silva Filipe, Ana
Fletcher, Tom
Green, Christopher A
Harrison, Ewen M
Hiscox, Julian A
Ho, Antonia Ying Wai
Horby, Peter W
Ijaz, Samreen
Khoo, Saye
Klenerman, Paul
Law, Andrew
Lim, Wei Shen
Mentzer, Alexander J
Merson, Laura
Meynert, Alison M
Noursadeghi, Mahdad
Moore, Shona C
Palmarini, Massimo
Paxton, William A
Pollakis, Georgios
Price, Nicholas
Rambaut, Andrew
Robertson, David L
Russell, Clark D
Sancho-Shimizu, Vanessa
Scott, Janet T
Sigfrid, Louise
Solomon, Tom
Sriskandan, Shiranee
Stuart, David
Summers, Charlotte
Tedder, Richard S
Thomson, Emma C
Thwaites, Ryan S
Turtle, Lance CW
Zambon, Maria
Hardwick, Hayley
Donohue, Chloe
Ewins, Jane
Oosthuyzen, Wilna
Griffiths, Fiona
Norman, Lisa
Pius, Riinu
Drake, Tom M
Fairfield, Cameron J
Knight, Stephen
Mclean, Kenneth A
Murphy, Derek
Shaw, Catherine A
Dalton, Jo
Girvan, Michelle
Saviciute, Egle
Roberts, Stephanie
Harrison, Janet
Marsh, Laura
Connor, Marie
Halpin, Sophie
Jackson, Clare
Gamble, Carrol
Leeming, Gary
Law, Andrew
Hendry, Ross
Scott-Brown, James
Greenhalf, William
Shaw, Victoria
McDonald, Sarah
Ahmed, Katie A
Armstrong, Jane A
Ashworth, Milton
Asiimwe, Innocent G
Bakshi, Siddharth
Barlow, Samantha L
Booth, Laura
Brennan, Benjamin
Bullock, Katie
Catterall, Benjamin WA
Clark, Jordan J
Clarke, Emily A
Cole, Sarah
Cooper, Louise
Cox, Helen
Davis, Christopher
Dincarslan, Oslem
Dunn, Chris
Dyer, Philip
Elliott, Angela
Evans, Anthony
Fisher, Lewis WS
Foster, Terry
Garcia-Dorival, Isabel
Greenhalf, Willliam
Gunning, Philip
Hartley, Catherine
Ho, Antonia
Jensen, Rebecca L
Jones, Christopher B
Jones, Trevor R
Khandaker, Shadia
King, Katharine
Kiy, Robyn T
Koukorava, Chrysa
Lake, Annette
Lant, Suzannah
Latawiec, Diane
Lavelle-Langham, L
Lefteri, Daniella
Lett, Lauren
Livoti, Lucia A
Mancini, Maria
McDonald, Sarah
McEvoy, Laurence
McLauchlan, John
Metelmann, Soeren
Miah, Nahida S
Middleton, Joanna
Mitchell, Joyce
Moore, Shona C
Murphy, Ellen G
Penrice-Randal, Rebekah
Pilgrim, Jack
Prince, Tessa
Reynolds, Will
Ridley, P Matthew
Sales, Debby
Shaw, Victoria E
Shears, Rebecca K
Small, Benjamin
Subramaniam, Krishanthi S
Szemiel, Agnieska
Taggart, Aislynn
Tanianis-Hughes, Jolanta
Thomas, Jordan
Trochu, Erwan
van Tonder, Libby
Wilcock, Eve
Zhang, J Eunice
Adeniji, Kayode
Agranoff, Daniel
Agwuh, Ken
Ail, Dhiraj
Alegria, Ana
Angus, Brian
Ashish, Abdul
Atkinson, Dougal
Bari, Shahedal
Barlow, Gavin
Barnass, Stella
Barrett, Nicholas
Bassford, Christopher
Baxter, David
Beadsworth, Michael
Bernatoniene, Jolanta
Berridge, John
Best, Nicola
Bothma, Pieter
Brealey, David
Brittain-Long, Robin
Bulteel, Naomi
Burden, Tom
Burtenshaw, Andrew
Caruth, Vikki
Chadwick, David
Chambler, Duncan
Chee, Nigel
Child, Jenny
Chukkambotla, Srikanth
Clark, Tom
Collini, Paul
Cosgrove, Catherine
Cupitt, Jason
Cutino-Moguel, Maria-Teresa
Dark, Paul
Dawson, Chris
Dervisevic, Samir
Donnison, Phil
Douthwaite, Sam
DuRand, Ingrid
Dushianthan, Ahilanadan
Dyer, Tristan
Evans, Cariad
Eziefula, Chi
Fegan, Chrisopher
Finn, Adam
Fullerton, Duncan
Garg, Sanjeev
Garg, Sanjeev
Garg, Atul
Godden, Jo
Goldsmith, Arthur
Graham, Clive
Hardy, Elaine
Hartshorn, Stuart
Harvey, Daniel
Havalda, Peter
Hawcutt, Daniel B
Hobrok, Maria
Hodgson, Luke
Holme, Anita
Hormis, Anil
Jacobs, Michael
Jain, Susan
Jennings, Paul
Kaliappan, Agilan
Kasipandian, Vidya
Kegg, Stephen
Kelsey, Michael
Kendall, Jason
Kerrison, Caroline
Kerslake, Ian
Koch, Oliver
Koduri, Gouri
Koshy, George
Laha, Shondipon
Larkin, Susan
Leiner, Tamas
Lillie, Patrick
Limb, James
Linnett, Vanessa
Little, Jeff
MacMahon, Michael
MacNaughton, Emily
Mankregod, Ravish
Masson, Huw
Matovu, Elijah
McCullough, Katherine
McEwen, Ruth
Meda, Manjula
Mills, Gary
Minton, Jane
Mirfenderesky, Mariyam
Mohandas, Kavya
Mok, Quen
Moon, James
Moore, Elinoor
Morgan, Patrick
Morris, Craig
Mortimore, Katherine
Moses, Samuel
Mpenge, Mbiye
Mulla, Rohinton
Murphy, Michael
Nagel, Megan
Nagarajan, Thapas
Nelson, Mark
Otahal, Igor
Pais, Mark
Panchatsharam, Selva
Paraiso, Hassan
Patel, Brij
Pepperell, Justin
Peters, Mark
Phull, Mandeep
Pintus, Stefania
Pooni, Jagtur Singh
Post, Frank
Price, David
Prout, Rachel
Rae, Nikolas
Reschreiter, Henrik
Reynolds, Tim
Richardson, Neil
Roberts, Mark
Roberts, Devender
Rose, Alistair
Rousseau, Guy
Ryan, Brendan
Saluja, Taranprit
Shah, Aarti
Shanmuga, Prad
Sharma, Anil
Shawcross, Anna
Sizer, Jeremy
Smith, Richard
Snelson, Catherine
Spittle, Nick
Staines, Nikki
Stambach, Tom
Stewart, Richard
Subudhi, Pradeep
Szakmany, Tamas
Tatham, Kate
Thomas, Jo
Thompson, Chris
Thompson, Robert
Tridente, Ascanio
Tupper-Carey, Darell
Twagira, Mary
Ustianowski, Andrew
Vallotton, Nick
Vincent-Smith, Lisa
Visuvanathan, Shico
Vuylsteke, Alan
Waddy, Sam
Wake, Rachel
Walden, Andrew
Welters, Ingeborg
Whitehouse, Tony
Whittaker, Paul
Whittington, Ashley
Wijesinghe, Meme
Williams, Martin
Wilson, Lawrence
Wilson, Sarah
Winchester, Stephen
Wiselka, Martin
Wolverson, Adam
Wooton, Daniel G
Workman, Andrew
Yates, Bryan
Young, Peter
author_sort Knight, Stephen R
collection PubMed
description OBJECTIVE: To develop and validate a pragmatic risk score to predict mortality in patients admitted to hospital with coronavirus disease 2019 (covid-19). DESIGN: Prospective observational cohort study. SETTING: International Severe Acute Respiratory and emerging Infections Consortium (ISARIC) World Health Organization (WHO) Clinical Characterisation Protocol UK (CCP-UK) study (performed by the ISARIC Coronavirus Clinical Characterisation Consortium—ISARIC-4C) in 260 hospitals across England, Scotland, and Wales. Model training was performed on a cohort of patients recruited between 6 February and 20 May 2020, with validation conducted on a second cohort of patients recruited after model development between 21 May and 29 June 2020. PARTICIPANTS: Adults (age ≥18 years) admitted to hospital with covid-19 at least four weeks before final data extraction. MAIN OUTCOME MEASURE: In-hospital mortality. RESULTS: 35 463 patients were included in the derivation dataset (mortality rate 32.2%) and 22 361 in the validation dataset (mortality rate 30.1%). The final 4C Mortality Score included eight variables readily available at initial hospital assessment: age, sex, number of comorbidities, respiratory rate, peripheral oxygen saturation, level of consciousness, urea level, and C reactive protein (score range 0-21 points). The 4C Score showed high discrimination for mortality (derivation cohort: area under the receiver operating characteristic curve 0.79, 95% confidence interval 0.78 to 0.79; validation cohort: 0.77, 0.76 to 0.77) with excellent calibration (validation: calibration-in-the-large=0, slope=1.0). Patients with a score of at least 15 (n=4158, 19%) had a 62% mortality (positive predictive value 62%) compared with 1% mortality for those with a score of 3 or less (n=1650, 7%; negative predictive value 99%). Discriminatory performance was higher than 15 pre-existing risk stratification scores (area under the receiver operating characteristic curve range 0.61-0.76), with scores developed in other covid-19 cohorts often performing poorly (range 0.63-0.73). CONCLUSIONS: An easy-to-use risk stratification score has been developed and validated based on commonly available parameters at hospital presentation. The 4C Mortality Score outperformed existing scores, showed utility to directly inform clinical decision making, and can be used to stratify patients admitted to hospital with covid-19 into different management groups. The score should be further validated to determine its applicability in other populations. STUDY REGISTRATION: ISRCTN66726260
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publisher BMJ Publishing Group Ltd.
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spelling pubmed-71164722020-12-11 Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score Knight, Stephen R Ho, Antonia Pius, Riinu Buchan, Iain Carson, Gail Drake, Thomas M Dunning, Jake Fairfield, Cameron J Gamble, Carrol Green, Christopher A Gupta, Rishi Halpin, Sophie Hardwick, Hayley E Holden, Karl A Horby, Peter W Jackson, Clare Mclean, Kenneth A Merson, Laura Nguyen-Van-Tam, Jonathan S Norman, Lisa Noursadeghi, Mahdad Olliaro, Piero L Pritchard, Mark G Russell, Clark D Shaw, Catherine A Sheikh, Aziz Solomon, Tom Sudlow, Cathie Swann, Olivia V Turtle, Lance CW Openshaw, Peter JM Baillie, J Kenneth Semple, Malcolm G Docherty, Annemarie B Harrison, Ewen M Baillie, J Kenneth Semple, Malcolm G Openshaw, Peter JM Carson, Gail Alex, Beatrice Bach, Benjamin Barclay, Wendy S Bogaert, Debby Chand, Meera Cooke, Graham S Docherty, Annemarie B Dunning, Jake da Silva Filipe, Ana Fletcher, Tom Green, Christopher A Harrison, Ewen M Hiscox, Julian A Ho, Antonia Ying Wai Horby, Peter W Ijaz, Samreen Khoo, Saye Klenerman, Paul Law, Andrew Lim, Wei Shen Mentzer, Alexander J Merson, Laura Meynert, Alison M Noursadeghi, Mahdad Moore, Shona C Palmarini, Massimo Paxton, William A Pollakis, Georgios Price, Nicholas Rambaut, Andrew Robertson, David L Russell, Clark D Sancho-Shimizu, Vanessa Scott, Janet T Sigfrid, Louise Solomon, Tom Sriskandan, Shiranee Stuart, David Summers, Charlotte Tedder, Richard S Thomson, Emma C Thwaites, Ryan S Turtle, Lance CW Zambon, Maria Hardwick, Hayley Donohue, Chloe Ewins, Jane Oosthuyzen, Wilna Griffiths, Fiona Norman, Lisa Pius, Riinu Drake, Tom M Fairfield, Cameron J Knight, Stephen Mclean, Kenneth A Murphy, Derek Shaw, Catherine A Dalton, Jo Girvan, Michelle Saviciute, Egle Roberts, Stephanie Harrison, Janet Marsh, Laura Connor, Marie Halpin, Sophie Jackson, Clare Gamble, Carrol Leeming, Gary Law, Andrew Hendry, Ross Scott-Brown, James Greenhalf, William Shaw, Victoria McDonald, Sarah Ahmed, Katie A Armstrong, Jane A Ashworth, Milton Asiimwe, Innocent G Bakshi, Siddharth Barlow, Samantha L Booth, Laura Brennan, Benjamin Bullock, Katie Catterall, Benjamin WA Clark, Jordan J Clarke, Emily A Cole, Sarah Cooper, Louise Cox, Helen Davis, Christopher Dincarslan, Oslem Dunn, Chris Dyer, Philip Elliott, Angela Evans, Anthony Fisher, Lewis WS Foster, Terry Garcia-Dorival, Isabel Greenhalf, Willliam Gunning, Philip Hartley, Catherine Ho, Antonia Jensen, Rebecca L Jones, Christopher B Jones, Trevor R Khandaker, Shadia King, Katharine Kiy, Robyn T Koukorava, Chrysa Lake, Annette Lant, Suzannah Latawiec, Diane Lavelle-Langham, L Lefteri, Daniella Lett, Lauren Livoti, Lucia A Mancini, Maria McDonald, Sarah McEvoy, Laurence McLauchlan, John Metelmann, Soeren Miah, Nahida S Middleton, Joanna Mitchell, Joyce Moore, Shona C Murphy, Ellen G Penrice-Randal, Rebekah Pilgrim, Jack Prince, Tessa Reynolds, Will Ridley, P Matthew Sales, Debby Shaw, Victoria E Shears, Rebecca K Small, Benjamin Subramaniam, Krishanthi S Szemiel, Agnieska Taggart, Aislynn Tanianis-Hughes, Jolanta Thomas, Jordan Trochu, Erwan van Tonder, Libby Wilcock, Eve Zhang, J Eunice Adeniji, Kayode Agranoff, Daniel Agwuh, Ken Ail, Dhiraj Alegria, Ana Angus, Brian Ashish, Abdul Atkinson, Dougal Bari, Shahedal Barlow, Gavin Barnass, Stella Barrett, Nicholas Bassford, Christopher Baxter, David Beadsworth, Michael Bernatoniene, Jolanta Berridge, John Best, Nicola Bothma, Pieter Brealey, David Brittain-Long, Robin Bulteel, Naomi Burden, Tom Burtenshaw, Andrew Caruth, Vikki Chadwick, David Chambler, Duncan Chee, Nigel Child, Jenny Chukkambotla, Srikanth Clark, Tom Collini, Paul Cosgrove, Catherine Cupitt, Jason Cutino-Moguel, Maria-Teresa Dark, Paul Dawson, Chris Dervisevic, Samir Donnison, Phil Douthwaite, Sam DuRand, Ingrid Dushianthan, Ahilanadan Dyer, Tristan Evans, Cariad Eziefula, Chi Fegan, Chrisopher Finn, Adam Fullerton, Duncan Garg, Sanjeev Garg, Sanjeev Garg, Atul Godden, Jo Goldsmith, Arthur Graham, Clive Hardy, Elaine Hartshorn, Stuart Harvey, Daniel Havalda, Peter Hawcutt, Daniel B Hobrok, Maria Hodgson, Luke Holme, Anita Hormis, Anil Jacobs, Michael Jain, Susan Jennings, Paul Kaliappan, Agilan Kasipandian, Vidya Kegg, Stephen Kelsey, Michael Kendall, Jason Kerrison, Caroline Kerslake, Ian Koch, Oliver Koduri, Gouri Koshy, George Laha, Shondipon Larkin, Susan Leiner, Tamas Lillie, Patrick Limb, James Linnett, Vanessa Little, Jeff MacMahon, Michael MacNaughton, Emily Mankregod, Ravish Masson, Huw Matovu, Elijah McCullough, Katherine McEwen, Ruth Meda, Manjula Mills, Gary Minton, Jane Mirfenderesky, Mariyam Mohandas, Kavya Mok, Quen Moon, James Moore, Elinoor Morgan, Patrick Morris, Craig Mortimore, Katherine Moses, Samuel Mpenge, Mbiye Mulla, Rohinton Murphy, Michael Nagel, Megan Nagarajan, Thapas Nelson, Mark Otahal, Igor Pais, Mark Panchatsharam, Selva Paraiso, Hassan Patel, Brij Pepperell, Justin Peters, Mark Phull, Mandeep Pintus, Stefania Pooni, Jagtur Singh Post, Frank Price, David Prout, Rachel Rae, Nikolas Reschreiter, Henrik Reynolds, Tim Richardson, Neil Roberts, Mark Roberts, Devender Rose, Alistair Rousseau, Guy Ryan, Brendan Saluja, Taranprit Shah, Aarti Shanmuga, Prad Sharma, Anil Shawcross, Anna Sizer, Jeremy Smith, Richard Snelson, Catherine Spittle, Nick Staines, Nikki Stambach, Tom Stewart, Richard Subudhi, Pradeep Szakmany, Tamas Tatham, Kate Thomas, Jo Thompson, Chris Thompson, Robert Tridente, Ascanio Tupper-Carey, Darell Twagira, Mary Ustianowski, Andrew Vallotton, Nick Vincent-Smith, Lisa Visuvanathan, Shico Vuylsteke, Alan Waddy, Sam Wake, Rachel Walden, Andrew Welters, Ingeborg Whitehouse, Tony Whittaker, Paul Whittington, Ashley Wijesinghe, Meme Williams, Martin Wilson, Lawrence Wilson, Sarah Winchester, Stephen Wiselka, Martin Wolverson, Adam Wooton, Daniel G Workman, Andrew Yates, Bryan Young, Peter BMJ Research OBJECTIVE: To develop and validate a pragmatic risk score to predict mortality in patients admitted to hospital with coronavirus disease 2019 (covid-19). DESIGN: Prospective observational cohort study. SETTING: International Severe Acute Respiratory and emerging Infections Consortium (ISARIC) World Health Organization (WHO) Clinical Characterisation Protocol UK (CCP-UK) study (performed by the ISARIC Coronavirus Clinical Characterisation Consortium—ISARIC-4C) in 260 hospitals across England, Scotland, and Wales. Model training was performed on a cohort of patients recruited between 6 February and 20 May 2020, with validation conducted on a second cohort of patients recruited after model development between 21 May and 29 June 2020. PARTICIPANTS: Adults (age ≥18 years) admitted to hospital with covid-19 at least four weeks before final data extraction. MAIN OUTCOME MEASURE: In-hospital mortality. RESULTS: 35 463 patients were included in the derivation dataset (mortality rate 32.2%) and 22 361 in the validation dataset (mortality rate 30.1%). The final 4C Mortality Score included eight variables readily available at initial hospital assessment: age, sex, number of comorbidities, respiratory rate, peripheral oxygen saturation, level of consciousness, urea level, and C reactive protein (score range 0-21 points). The 4C Score showed high discrimination for mortality (derivation cohort: area under the receiver operating characteristic curve 0.79, 95% confidence interval 0.78 to 0.79; validation cohort: 0.77, 0.76 to 0.77) with excellent calibration (validation: calibration-in-the-large=0, slope=1.0). Patients with a score of at least 15 (n=4158, 19%) had a 62% mortality (positive predictive value 62%) compared with 1% mortality for those with a score of 3 or less (n=1650, 7%; negative predictive value 99%). Discriminatory performance was higher than 15 pre-existing risk stratification scores (area under the receiver operating characteristic curve range 0.61-0.76), with scores developed in other covid-19 cohorts often performing poorly (range 0.63-0.73). CONCLUSIONS: An easy-to-use risk stratification score has been developed and validated based on commonly available parameters at hospital presentation. The 4C Mortality Score outperformed existing scores, showed utility to directly inform clinical decision making, and can be used to stratify patients admitted to hospital with covid-19 into different management groups. The score should be further validated to determine its applicability in other populations. STUDY REGISTRATION: ISRCTN66726260 BMJ Publishing Group Ltd. 2020-09-09 /pmc/articles/PMC7116472/ /pubmed/32907855 http://dx.doi.org/10.1136/bmj.m3339 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research
Knight, Stephen R
Ho, Antonia
Pius, Riinu
Buchan, Iain
Carson, Gail
Drake, Thomas M
Dunning, Jake
Fairfield, Cameron J
Gamble, Carrol
Green, Christopher A
Gupta, Rishi
Halpin, Sophie
Hardwick, Hayley E
Holden, Karl A
Horby, Peter W
Jackson, Clare
Mclean, Kenneth A
Merson, Laura
Nguyen-Van-Tam, Jonathan S
Norman, Lisa
Noursadeghi, Mahdad
Olliaro, Piero L
Pritchard, Mark G
Russell, Clark D
Shaw, Catherine A
Sheikh, Aziz
Solomon, Tom
Sudlow, Cathie
Swann, Olivia V
Turtle, Lance CW
Openshaw, Peter JM
Baillie, J Kenneth
Semple, Malcolm G
Docherty, Annemarie B
Harrison, Ewen M
Baillie, J Kenneth
Semple, Malcolm G
Openshaw, Peter JM
Carson, Gail
Alex, Beatrice
Bach, Benjamin
Barclay, Wendy S
Bogaert, Debby
Chand, Meera
Cooke, Graham S
Docherty, Annemarie B
Dunning, Jake
da Silva Filipe, Ana
Fletcher, Tom
Green, Christopher A
Harrison, Ewen M
Hiscox, Julian A
Ho, Antonia Ying Wai
Horby, Peter W
Ijaz, Samreen
Khoo, Saye
Klenerman, Paul
Law, Andrew
Lim, Wei Shen
Mentzer, Alexander J
Merson, Laura
Meynert, Alison M
Noursadeghi, Mahdad
Moore, Shona C
Palmarini, Massimo
Paxton, William A
Pollakis, Georgios
Price, Nicholas
Rambaut, Andrew
Robertson, David L
Russell, Clark D
Sancho-Shimizu, Vanessa
Scott, Janet T
Sigfrid, Louise
Solomon, Tom
Sriskandan, Shiranee
Stuart, David
Summers, Charlotte
Tedder, Richard S
Thomson, Emma C
Thwaites, Ryan S
Turtle, Lance CW
Zambon, Maria
Hardwick, Hayley
Donohue, Chloe
Ewins, Jane
Oosthuyzen, Wilna
Griffiths, Fiona
Norman, Lisa
Pius, Riinu
Drake, Tom M
Fairfield, Cameron J
Knight, Stephen
Mclean, Kenneth A
Murphy, Derek
Shaw, Catherine A
Dalton, Jo
Girvan, Michelle
Saviciute, Egle
Roberts, Stephanie
Harrison, Janet
Marsh, Laura
Connor, Marie
Halpin, Sophie
Jackson, Clare
Gamble, Carrol
Leeming, Gary
Law, Andrew
Hendry, Ross
Scott-Brown, James
Greenhalf, William
Shaw, Victoria
McDonald, Sarah
Ahmed, Katie A
Armstrong, Jane A
Ashworth, Milton
Asiimwe, Innocent G
Bakshi, Siddharth
Barlow, Samantha L
Booth, Laura
Brennan, Benjamin
Bullock, Katie
Catterall, Benjamin WA
Clark, Jordan J
Clarke, Emily A
Cole, Sarah
Cooper, Louise
Cox, Helen
Davis, Christopher
Dincarslan, Oslem
Dunn, Chris
Dyer, Philip
Elliott, Angela
Evans, Anthony
Fisher, Lewis WS
Foster, Terry
Garcia-Dorival, Isabel
Greenhalf, Willliam
Gunning, Philip
Hartley, Catherine
Ho, Antonia
Jensen, Rebecca L
Jones, Christopher B
Jones, Trevor R
Khandaker, Shadia
King, Katharine
Kiy, Robyn T
Koukorava, Chrysa
Lake, Annette
Lant, Suzannah
Latawiec, Diane
Lavelle-Langham, L
Lefteri, Daniella
Lett, Lauren
Livoti, Lucia A
Mancini, Maria
McDonald, Sarah
McEvoy, Laurence
McLauchlan, John
Metelmann, Soeren
Miah, Nahida S
Middleton, Joanna
Mitchell, Joyce
Moore, Shona C
Murphy, Ellen G
Penrice-Randal, Rebekah
Pilgrim, Jack
Prince, Tessa
Reynolds, Will
Ridley, P Matthew
Sales, Debby
Shaw, Victoria E
Shears, Rebecca K
Small, Benjamin
Subramaniam, Krishanthi S
Szemiel, Agnieska
Taggart, Aislynn
Tanianis-Hughes, Jolanta
Thomas, Jordan
Trochu, Erwan
van Tonder, Libby
Wilcock, Eve
Zhang, J Eunice
Adeniji, Kayode
Agranoff, Daniel
Agwuh, Ken
Ail, Dhiraj
Alegria, Ana
Angus, Brian
Ashish, Abdul
Atkinson, Dougal
Bari, Shahedal
Barlow, Gavin
Barnass, Stella
Barrett, Nicholas
Bassford, Christopher
Baxter, David
Beadsworth, Michael
Bernatoniene, Jolanta
Berridge, John
Best, Nicola
Bothma, Pieter
Brealey, David
Brittain-Long, Robin
Bulteel, Naomi
Burden, Tom
Burtenshaw, Andrew
Caruth, Vikki
Chadwick, David
Chambler, Duncan
Chee, Nigel
Child, Jenny
Chukkambotla, Srikanth
Clark, Tom
Collini, Paul
Cosgrove, Catherine
Cupitt, Jason
Cutino-Moguel, Maria-Teresa
Dark, Paul
Dawson, Chris
Dervisevic, Samir
Donnison, Phil
Douthwaite, Sam
DuRand, Ingrid
Dushianthan, Ahilanadan
Dyer, Tristan
Evans, Cariad
Eziefula, Chi
Fegan, Chrisopher
Finn, Adam
Fullerton, Duncan
Garg, Sanjeev
Garg, Sanjeev
Garg, Atul
Godden, Jo
Goldsmith, Arthur
Graham, Clive
Hardy, Elaine
Hartshorn, Stuart
Harvey, Daniel
Havalda, Peter
Hawcutt, Daniel B
Hobrok, Maria
Hodgson, Luke
Holme, Anita
Hormis, Anil
Jacobs, Michael
Jain, Susan
Jennings, Paul
Kaliappan, Agilan
Kasipandian, Vidya
Kegg, Stephen
Kelsey, Michael
Kendall, Jason
Kerrison, Caroline
Kerslake, Ian
Koch, Oliver
Koduri, Gouri
Koshy, George
Laha, Shondipon
Larkin, Susan
Leiner, Tamas
Lillie, Patrick
Limb, James
Linnett, Vanessa
Little, Jeff
MacMahon, Michael
MacNaughton, Emily
Mankregod, Ravish
Masson, Huw
Matovu, Elijah
McCullough, Katherine
McEwen, Ruth
Meda, Manjula
Mills, Gary
Minton, Jane
Mirfenderesky, Mariyam
Mohandas, Kavya
Mok, Quen
Moon, James
Moore, Elinoor
Morgan, Patrick
Morris, Craig
Mortimore, Katherine
Moses, Samuel
Mpenge, Mbiye
Mulla, Rohinton
Murphy, Michael
Nagel, Megan
Nagarajan, Thapas
Nelson, Mark
Otahal, Igor
Pais, Mark
Panchatsharam, Selva
Paraiso, Hassan
Patel, Brij
Pepperell, Justin
Peters, Mark
Phull, Mandeep
Pintus, Stefania
Pooni, Jagtur Singh
Post, Frank
Price, David
Prout, Rachel
Rae, Nikolas
Reschreiter, Henrik
Reynolds, Tim
Richardson, Neil
Roberts, Mark
Roberts, Devender
Rose, Alistair
Rousseau, Guy
Ryan, Brendan
Saluja, Taranprit
Shah, Aarti
Shanmuga, Prad
Sharma, Anil
Shawcross, Anna
Sizer, Jeremy
Smith, Richard
Snelson, Catherine
Spittle, Nick
Staines, Nikki
Stambach, Tom
Stewart, Richard
Subudhi, Pradeep
Szakmany, Tamas
Tatham, Kate
Thomas, Jo
Thompson, Chris
Thompson, Robert
Tridente, Ascanio
Tupper-Carey, Darell
Twagira, Mary
Ustianowski, Andrew
Vallotton, Nick
Vincent-Smith, Lisa
Visuvanathan, Shico
Vuylsteke, Alan
Waddy, Sam
Wake, Rachel
Walden, Andrew
Welters, Ingeborg
Whitehouse, Tony
Whittaker, Paul
Whittington, Ashley
Wijesinghe, Meme
Williams, Martin
Wilson, Lawrence
Wilson, Sarah
Winchester, Stephen
Wiselka, Martin
Wolverson, Adam
Wooton, Daniel G
Workman, Andrew
Yates, Bryan
Young, Peter
Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score
title Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score
title_full Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score
title_fullStr Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score
title_full_unstemmed Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score
title_short Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score
title_sort risk stratification of patients admitted to hospital with covid-19 using the isaric who clinical characterisation protocol: development and validation of the 4c mortality score
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116472/
https://www.ncbi.nlm.nih.gov/pubmed/32907855
http://dx.doi.org/10.1136/bmj.m3339
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AT meynertalisonm riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT noursadeghimahdad riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mooreshonac riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT palmarinimassimo riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT paxtonwilliama riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT pollakisgeorgios riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT pricenicholas riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT rambautandrew riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT robertsondavidl riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT russellclarkd riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT sanchoshimizuvanessa riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT scottjanett riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT sigfridlouise riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT solomontom riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT sriskandanshiranee riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT stuartdavid riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT summerscharlotte riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT tedderrichards riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT thomsonemmac riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT thwaitesryans riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT turtlelancecw riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT zambonmaria riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT hardwickhayley riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT donohuechloe riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT ewinsjane riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT oosthuyzenwilna riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT griffithsfiona riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT normanlisa riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT piusriinu riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT draketomm riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT fairfieldcameronj riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT knightstephen riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mcleankennetha riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT murphyderek riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT shawcatherinea riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT daltonjo riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT girvanmichelle riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT saviciuteegle riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT robertsstephanie riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT harrisonjanet riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT marshlaura riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT connormarie riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT halpinsophie riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT jacksonclare riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT gamblecarrol riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT leeminggary riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT lawandrew riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT hendryross riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT scottbrownjames riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT greenhalfwilliam riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT shawvictoria riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mcdonaldsarah riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT ahmedkatiea riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT armstrongjanea riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT ashworthmilton riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT asiimweinnocentg riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT bakshisiddharth riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT barlowsamanthal riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT boothlaura riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT brennanbenjamin riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT bullockkatie riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT catterallbenjaminwa riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT clarkjordanj riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT clarkeemilya riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT colesarah riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT cooperlouise riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT coxhelen riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT davischristopher riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT dincarslanoslem riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT dunnchris riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT dyerphilip riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT elliottangela riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT evansanthony riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT fisherlewisws riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT fosterterry riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT garciadorivalisabel riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT greenhalfwillliam riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT gunningphilip riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT hartleycatherine riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT hoantonia riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT jensenrebeccal riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT joneschristopherb riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT jonestrevorr riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT khandakershadia riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT kingkatharine riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT kiyrobynt riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT koukoravachrysa riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT lakeannette riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT lantsuzannah riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT latawiecdiane riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT lavellelanghaml riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT lefteridaniella riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT lettlauren riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT livotiluciaa riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mancinimaria riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mcdonaldsarah riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mcevoylaurence riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mclauchlanjohn riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT metelmannsoeren riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT miahnahidas riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT middletonjoanna riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mitchelljoyce riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mooreshonac riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT murphyelleng riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT penricerandalrebekah riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT pilgrimjack riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT princetessa riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT reynoldswill riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT ridleypmatthew riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT salesdebby riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT shawvictoriae riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT shearsrebeccak riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT smallbenjamin riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT subramaniamkrishanthis riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT szemielagnieska riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT taggartaislynn riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT tanianishughesjolanta riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT thomasjordan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT trochuerwan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT vantonderlibby riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT wilcockeve riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT zhangjeunice riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT adenijikayode riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT agranoffdaniel riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT agwuhken riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT aildhiraj riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT alegriaana riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT angusbrian riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT ashishabdul riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT atkinsondougal riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT barishahedal riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT barlowgavin riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT barnassstella riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT barrettnicholas riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT bassfordchristopher riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT baxterdavid riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT beadsworthmichael riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT bernatonienejolanta riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT berridgejohn riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT bestnicola riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT bothmapieter riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT brealeydavid riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT brittainlongrobin riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT bulteelnaomi riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT burdentom riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT burtenshawandrew riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT caruthvikki riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT chadwickdavid riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT chamblerduncan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT cheenigel riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT childjenny riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT chukkambotlasrikanth riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT clarktom riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT collinipaul riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT cosgrovecatherine riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT cupittjason riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT cutinomoguelmariateresa riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT darkpaul riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT dawsonchris riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT dervisevicsamir riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT donnisonphil riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT douthwaitesam riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT durandingrid riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT dushianthanahilanadan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT dyertristan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT evanscariad riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT eziefulachi riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT feganchrisopher riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT finnadam riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT fullertonduncan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT gargsanjeev riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT gargsanjeev riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT gargatul riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT goddenjo riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT goldsmitharthur riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT grahamclive riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT hardyelaine riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT hartshornstuart riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT harveydaniel riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT havaldapeter riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT hawcuttdanielb riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT hobrokmaria riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT hodgsonluke riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT holmeanita riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT hormisanil riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT jacobsmichael riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT jainsusan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT jenningspaul riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT kaliappanagilan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT kasipandianvidya riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT keggstephen riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT kelseymichael riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT kendalljason riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT kerrisoncaroline riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT kerslakeian riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT kocholiver riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT kodurigouri riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT koshygeorge riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT lahashondipon riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT larkinsusan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT leinertamas riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT lilliepatrick riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT limbjames riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT linnettvanessa riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT littlejeff riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT macmahonmichael riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT macnaughtonemily riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mankregodravish riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT massonhuw riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT matovuelijah riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mcculloughkatherine riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mcewenruth riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT medamanjula riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT millsgary riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mintonjane riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mirfendereskymariyam riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mohandaskavya riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mokquen riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT moonjames riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mooreelinoor riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT morganpatrick riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT morriscraig riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mortimorekatherine riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mosessamuel riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mpengembiye riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT mullarohinton riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT murphymichael riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT nagelmegan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT nagarajanthapas riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT nelsonmark riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT otahaligor riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT paismark riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT panchatsharamselva riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT paraisohassan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT patelbrij riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT pepperelljustin riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT petersmark riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT phullmandeep riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT pintusstefania riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT poonijagtursingh riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT postfrank riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT pricedavid riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT proutrachel riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT raenikolas riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT reschreiterhenrik riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT reynoldstim riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT richardsonneil riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT robertsmark riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT robertsdevender riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT rosealistair riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT rousseauguy riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT ryanbrendan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT salujataranprit riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT shahaarti riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT shanmugaprad riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT sharmaanil riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT shawcrossanna riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT sizerjeremy riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT smithrichard riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT snelsoncatherine riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT spittlenick riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT stainesnikki riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT stambachtom riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT stewartrichard riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT subudhipradeep riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT szakmanytamas riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT tathamkate riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT thomasjo riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT thompsonchris riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT thompsonrobert riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT tridenteascanio riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT tuppercareydarell riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT twagiramary riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT ustianowskiandrew riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT vallottonnick riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT vincentsmithlisa riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT visuvanathanshico riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT vuylstekealan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT waddysam riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT wakerachel riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT waldenandrew riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT weltersingeborg riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT whitehousetony riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT whittakerpaul riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT whittingtonashley riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT wijesinghememe riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT williamsmartin riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT wilsonlawrence riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT wilsonsarah riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT winchesterstephen riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT wiselkamartin riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT wolversonadam riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT wootondanielg riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT workmanandrew riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT yatesbryan riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore
AT youngpeter riskstratificationofpatientsadmittedtohospitalwithcovid19usingtheisaricwhoclinicalcharacterisationprotocoldevelopmentandvalidationofthe4cmortalityscore