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Insights into genetic variants associated with NASH-fibrosis from metabolite profiling
Several genetic discoveries robustly implicate five single-nucleotide variants in the progression of non-alcoholic fatty liver disease to non-alcoholic steatohepatitis and fibrosis (NASH-fibrosis), including a recently identified variant in MTARC1. To better understand these variants as potential th...
Autores principales: | Mann, Jake P, Pietzner, Maik, Wittemans, Laura B, Rolfe, Emmanuela De Lucia, Kerrison, Nicola D, Imamura, Fumiaki, Forouhi, Nita G, Fauman, Eric, Allison, Michael E, Griffin, Jules L, Koulman, Albert, Wareham, Nicholas J, Langenberg, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116726/ https://www.ncbi.nlm.nih.gov/pubmed/32720691 http://dx.doi.org/10.1093/hmg/ddaa162 |
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