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Insights into genetic variants associated with NASH-fibrosis from metabolite profiling

Several genetic discoveries robustly implicate five single-nucleotide variants in the progression of non-alcoholic fatty liver disease to non-alcoholic steatohepatitis and fibrosis (NASH-fibrosis), including a recently identified variant in MTARC1. To better understand these variants as potential th...

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Detalles Bibliográficos
Autores principales: Mann, Jake P, Pietzner, Maik, Wittemans, Laura B, Rolfe, Emmanuela De Lucia, Kerrison, Nicola D, Imamura, Fumiaki, Forouhi, Nita G, Fauman, Eric, Allison, Michael E, Griffin, Jules L, Koulman, Albert, Wareham, Nicholas J, Langenberg, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116726/
https://www.ncbi.nlm.nih.gov/pubmed/32720691
http://dx.doi.org/10.1093/hmg/ddaa162

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