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Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

The papain-like protease PLpro is an essential coronavirus enzyme that is required for processing viral polyproteins to generate a functional replicase complex and enable viral spread(1,2). PLpro is also implicated in cleaving proteinaceous post-translational modifications on host proteins as an eva...

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Detalles Bibliográficos
Autores principales:	Shin, Donghyuk, Mukherjee, Rukmini, Grewe, Diana, Bojkova, Denisa, Baek, Kheewoong, Bhattacharya, Anshu, Schulz, Laura, Widera, Marek, Mehdipour, Ahmad Reza, Tascher, Georg, Geurink, Paul P., Wilhelm, Alexander, van der Heden van Noort, Gerbrand J., Ovaa, Huib, Müller, Stefan, Knobeloch, Klaus-Peter, Rajalingam, Krishnaraj, Schulman, Brenda A., Cinatl, Jindrich, Hummer, Gerhard, Ciesek, Sandra, Dikic, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116779/ https://www.ncbi.nlm.nih.gov/pubmed/32726803 http://dx.doi.org/10.1038/s41586-020-2601-5

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