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RAD51-dependent recruitment of TERRA lncRNA to telomeres through R-loops
Telomeres which are present at the ends of eukaryotic chromosomes mediate genome stability and determine cellular lifespan(1). Telomeric repeat containing RNAs (TERRA) are long noncoding RNAs transcribed from chromosome ends(2,3), which regulate telomeric chromatin structure and telomere maintenance...
Autores principales: | Feretzaki, Marianna, Pospíšilová, Michaela, Fernandes, Rita Valador, Lunardi, Thomas, Krejci, Lumir, Lingner, Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116795/ https://www.ncbi.nlm.nih.gov/pubmed/33057192 http://dx.doi.org/10.1038/s41586-020-2815-6 |
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