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RAD51-dependent recruitment of TERRA lncRNA to telomeres through R-loops

Telomeres which are present at the ends of eukaryotic chromosomes mediate genome stability and determine cellular lifespan(1). Telomeric repeat containing RNAs (TERRA) are long noncoding RNAs transcribed from chromosome ends(2,3), which regulate telomeric chromatin structure and telomere maintenance...

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Detalles Bibliográficos
Autores principales: Feretzaki, Marianna, Pospíšilová, Michaela, Fernandes, Rita Valador, Lunardi, Thomas, Krejci, Lumir, Lingner, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116795/
https://www.ncbi.nlm.nih.gov/pubmed/33057192
http://dx.doi.org/10.1038/s41586-020-2815-6

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