Red blood cell tension protects against severe malaria in the Dantu blood group

Malaria has had a major effect on the human genome, many protective polymorphisms such as sickle cell trait having been selected to high frequencies in malaria endemic regions(1,2). Recently, it was shown that the blood group variant Dantu provides 74% protection against all forms of severe malaria...

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Detalles Bibliográficos
Autores principales: Kariuki, Silvia N., Marin-Menendez, Alejandro, Introini, Viola, Ravenhill, Benjamin J., Lin, Yen-Chun, Macharia, Alex, Makale, Johnstone, Tendwa, Metrine, Nyamu, Wilfred, Kotar, Jurij, Carrasquilla, Manuela, Rowe, J. Alexandra, Rockett, Kirk, Kwiatkowski, Dominic, Weekes, Michael P., Cicuta, Pietro, Williams, Thomas N., Rayner, Julian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116803/
https://www.ncbi.nlm.nih.gov/pubmed/32939086
http://dx.doi.org/10.1038/s41586-020-2726-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116803/
https://www.ncbi.nlm.nih.gov/pubmed/32939086
http://dx.doi.org/10.1038/s41586-020-2726-6

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