Cargando…

Red blood cell tension protects against severe malaria in the Dantu blood group

Malaria has had a major effect on the human genome, many protective polymorphisms such as sickle cell trait having been selected to high frequencies in malaria endemic regions(1,2). Recently, it was shown that the blood group variant Dantu provides 74% protection against all forms of severe malaria...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kariuki, Silvia N., Marin-Menendez, Alejandro, Introini, Viola, Ravenhill, Benjamin J., Lin, Yen-Chun, Macharia, Alex, Makale, Johnstone, Tendwa, Metrine, Nyamu, Wilfred, Kotar, Jurij, Carrasquilla, Manuela, Rowe, J. Alexandra, Rockett, Kirk, Kwiatkowski, Dominic, Weekes, Michael P., Cicuta, Pietro, Williams, Thomas N., Rayner, Julian C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116803/ https://www.ncbi.nlm.nih.gov/pubmed/32939086 http://dx.doi.org/10.1038/s41586-020-2726-6

Ejemplares similares

The Dantu blood group prevents parasite growth in vivo: Evidence from a controlled human malaria infection study
por: Kariuki, Silvia N, et al.
Publicado: (2023)

β‐Thalassemia pathogenic variants in a cohort of children from the East African coast
por: Macharia, Alexander W., et al.
Publicado: (2020)

Blood Pressure and Arterial Stiffness in Kenyan Adolescents With α(+)Thalassemia
por: Etyang, Anthony O., et al.
Publicado: (2017)

Biophysical Tools and Concepts Enable Understanding of Asexual Blood Stage Malaria
por: Introini, Viola, et al.
Publicado: (2022)

The clinical epidemiology of sickle cell anemia In Africa
por: Macharia, Alex W., et al.
Publicado: (2017)

Thermophoretic migration of vesicles depends on mean temperature and head group chemistry
por: Talbot, Emma L., et al.
Publicado: (2017)

Genetic determinants of glucose-6-phosphate dehydrogenase activity in Kenya
por: Shah, Shivang S, et al.
Publicado: (2014)

The epidemiology of sickle cell disease in children recruited in infancy in Kilifi, Kenya: a prospective cohort study
por: Uyoga, Sophie, et al.
Publicado: (2019)

The impact of malaria-protective red blood cell polymorphisms on parasite biomass in children with severe Plasmodium falciparum malaria
por: Uyoga, S., et al.
Publicado: (2022)

Volume and porosity thermal regulation in lipid mesophases by coupling mobile ligands to soft membranes
por: Parolini, Lucia, et al.
Publicado: (2015)

Long-range interactions, wobbles, and phase defects in chains of model cilia
por: Brumley, Douglas R., et al.
Publicado: (2016)

Entrainment of mammalian motile cilia in the brain with hydrodynamic forces
por: Pellicciotta, Nicola, et al.
Publicado: (2020)

Cilia density and flow velocity affect alignment of motile cilia from brain cells
por: Pellicciotta, Nicola, et al.
Publicado: (2020)

Assessing motile cilia coverage and beat frequency in mammalian in vitro cell culture tissues
por: Fradique, Ricardo, et al.
Publicado: (2023)

Reaction–Diffusion Patterning of DNA-Based Artificial Cells
por: Leathers, Adrian, et al.
Publicado: (2022)

Blood Pressure and Arterial Stiffness in Kenyan Adolescents With the Sickle Cell Trait
por: Etyang, Anthony O, et al.
Publicado: (2018)

The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion
por: Introini, Viola, et al.
Publicado: (2022)

Mechanistic Studies of the Negative Epistatic Malaria-protective Interaction Between Sickle Cell Trait and α(+)thalassemia
por: Herbert Opi, D., et al.
Publicado: (2014)

Erratum to “Mechanistic Studies of the Negative Epistatic Malaria-protective Interaction Between Sickle Cell Trait and α(+)thalassemia” [EBioMedicine 1 (2014) 29–36]
por: Opi, D. Herbert, et al.
Publicado: (2015)

Phenotyping ciliary dynamics and coordination in response to CFTR-modulators in Cystic Fibrosis respiratory epithelial cells
por: Chioccioli, M., et al.
Publicado: (2019)

Non-O ABO blood group genotypes differ in their associations with Plasmodium falciparum rosetting and severe malaria
por: Opi, D. Herbert, et al.
Publicado: (2023)

Centripetal nuclear shape fluctuations associate with chromatin condensation in early prophase
por: Introini, Viola, et al.
Publicado: (2023)

Pooled testing conserves SARS-CoV-2 laboratory resources and improves test turn-around time: experience on the Kenyan Coast
por: Agoti, Charles N., et al.
Publicado: (2021)

Case Report: β-thalassemia major on the East African coast
por: Macharia, Alexander W., et al.
Publicado: (2022)

Comprehensive cell surface proteomics defines markers of classical, intermediate and non-classical monocytes
por: Ravenhill, Benjamin J., et al.
Publicado: (2020)

No Evidence that Knops Blood Group Polymorphisms Affect Complement Receptor 1 Clustering on Erythrocytes
por: Swann, O. V., et al.
Publicado: (2017)

The structure of a Plasmodium vivax Tryptophan Rich Antigen domain suggests a lipid binding function for a pan-Plasmodium multi-gene family
por: Kundu, Prasun, et al.
Publicado: (2023)

Environmental Correlation Analysis for Genes Associated with Protection against Malaria
por: Mackinnon, Margaret J., et al.
Publicado: (2016)

The burden and consequences of inherited blood disorders among young children in western Kenya
por: Suchdev, Parminder S., et al.
Publicado: (2012)

Glucose-6-phosphate dehydrogenase deficiency and the risk of malaria and other diseases in children in Kenya: a case-control and a cohort study
por: Uyoga, Sophie, et al.
Publicado: (2015)

Plasma Plasmodium falciparum Histidine-rich Protein 2 Concentrations in Children With Malaria Infections of Differing Severity in Kilifi, Kenya
por: Uyoga, Sophie, et al.
Publicado: (2020)

The Oxygen Tension in the Placental Bloods of Goats
por: Prystowsky, Harry, et al.
Publicado: (1960)

Red blood cell complement receptor one level varies with Knops blood group, α(+)thalassaemia and age among Kenyan children
por: Opi, D H, et al.
Publicado: (2016)

Single-cell analysis of CD4+ T-cell differentiation reveals three major cell states and progressive acceleration of proliferation
por: Proserpio, Valentina, et al.
Publicado: (2016)

Occult hepatitis B virus infections and risk factors among school-going adolescent voluntary blood donors in Kwale County Kenya, January 2020–June 2021: Cross sectional study
por: Wahome, Peter Kitemi, et al.
Publicado: (2022)

Respiratory oscillations in alveolar oxygen tension measured in arterial blood
por: Formenti, Federico, et al.
Publicado: (2017)

Ventilation
por: Ravenhill, Alice
Publicado: (1899)

Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification
por: Oyola, Samuel O., et al.
Publicado: (2016)

Ocular Blood Flow and Normal Tension Glaucoma
por: Fan, Ning, et al.
Publicado: (2015)

High-speed shaking of frozen blood clots for extraction of human and malaria parasite DNA
por: Lundblom, Klara, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ff2okjuanjap3v1ksr2j8pmmbj