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Central and peripheral GLP-1 systems independently suppress eating

The anorexigenic peptide glucagon-like peptide-1 (GLP-1) is secreted from gut enteroendocrine cells and brain preproglucagon (PPG) neurons, which respectively define the peripheral and central GLP-1 systems. PPG neurons in the nucleus tractus solitarii (NTS) are widely assumed to link the peripheral...

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Detalles Bibliográficos
Autores principales: Brierley, Daniel I., Holt, Marie K., Singh, Arashdeep, de Araujo, Alan, McDougle, Molly, Vergara, Macarena, Afaghani, Majd H., Lee, Shin Jae, Scott, Karen, Maske, Calyn, Langhans, Wolfgang, Krause, Eric, de Kloet, Annette, Gribble, Fiona M., Reimann, Frank, Rinaman, Linda, de Lartigue, Guillaume, Trapp, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116821/
https://www.ncbi.nlm.nih.gov/pubmed/33589843
http://dx.doi.org/10.1038/s42255-021-00344-4