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Central and peripheral GLP-1 systems independently suppress eating
The anorexigenic peptide glucagon-like peptide-1 (GLP-1) is secreted from gut enteroendocrine cells and brain preproglucagon (PPG) neurons, which respectively define the peripheral and central GLP-1 systems. PPG neurons in the nucleus tractus solitarii (NTS) are widely assumed to link the peripheral...
Autores principales: | Brierley, Daniel I., Holt, Marie K., Singh, Arashdeep, de Araujo, Alan, McDougle, Molly, Vergara, Macarena, Afaghani, Majd H., Lee, Shin Jae, Scott, Karen, Maske, Calyn, Langhans, Wolfgang, Krause, Eric, de Kloet, Annette, Gribble, Fiona M., Reimann, Frank, Rinaman, Linda, de Lartigue, Guillaume, Trapp, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116821/ https://www.ncbi.nlm.nih.gov/pubmed/33589843 http://dx.doi.org/10.1038/s42255-021-00344-4 |
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