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Proteotoxic stress is a driver of the loser status and of cell competition
Cell competition allows “winner” cells to eliminate less fit “loser” cells in tissues. In Minute cell competition, cells heterozygous mutant in ribosome genes, such as RpS3 (+/-) cells, are eliminated by wild-type cells. How cells are primed as losers is partially understood and it has been proposed...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116823/ https://www.ncbi.nlm.nih.gov/pubmed/33495633 http://dx.doi.org/10.1038/s41556-020-00627-0 |