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Proteotoxic stress is a driver of the loser status and of cell competition

Cell competition allows “winner” cells to eliminate less fit “loser” cells in tissues. In Minute cell competition, cells heterozygous mutant in ribosome genes, such as RpS3 (+/-) cells, are eliminated by wild-type cells. How cells are primed as losers is partially understood and it has been proposed...

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Detalles Bibliográficos
Autores principales: Baumgartner, Michael E., Dinan, Michael P., Langton, Paul F., Kucinski, Iwo, Piddini, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116823/
https://www.ncbi.nlm.nih.gov/pubmed/33495633
http://dx.doi.org/10.1038/s41556-020-00627-0

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