Single-cell analyses reveal YAP/TAZ as regulators of stemness and cell plasticity in Glioblastoma

Glioblastoma (GBM) is a devastating human malignancy. GBM stem-like cells (GSCs) drive tumor initiation and progression. Yet, the molecular determinants defining GSCs in their native state in patients remain poorly understood. Here we used single cell datasets and identified GSCs at the apex of the...

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Detalles Bibliográficos
Autores principales: Castellan, Martina, Guarnieri, Alberto, Fujimura, Atsushi, Zanconato, Francesca, Battilana, Giusy, Panciera, Tito, Sladitschek, Hanna Lucie, Contessotto, Paolo, Citron, Anna, Grilli, Andrea, Romano, Oriana, Bicciato, Silvio, Fassan, Matteo, Porcù, Elena, Rosato, Antonio, Cordenonsi, Michelangelo, Piccolo, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116831/
https://www.ncbi.nlm.nih.gov/pubmed/33644767
http://dx.doi.org/10.1038/s43018-020-00150-z

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