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Space-time logic of liver gene expression at sublobular scale
The mammalian liver is a central hub for systemic metabolic homeostasis. Liver tissue is spatially structured, with hepatocytes operating in repeating lobules, and sub-lobule zones performing distinct functions. The liver is also subject to extensive temporal regulation, orchestrated by the interpla...
Autores principales: | Droin, Colas, El Kholtei, Jakob, Halpern, Keren Bahar, Hurni, Clémence, Rozenberg, Milena, Muvkadi, Sapir, Itzkovitz, Shalev, Naef, Felix |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116850/ https://www.ncbi.nlm.nih.gov/pubmed/33432202 http://dx.doi.org/10.1038/s42255-020-00323-1 |
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