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Structural basis for RIFIN-mediated activation of LILRB1 in malaria

The Plasmodium species that cause malaria are obligate intracellular parasites, and disease symptoms occur as they replicate within human blood. Despite risking immune detection, the parasite delivers proteins that bind host receptors to infected erythrocyte surfaces. In the causative agent of the m...

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Detalles Bibliográficos
Autores principales: Harrison, Thomas E., Mørch, Alexander M., Felce, James H., Sakoguchi, Akihito, Reid, Adam J., Arase, Hisashi, Dustin, Michael L., Higgins, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116854/
https://www.ncbi.nlm.nih.gov/pubmed/32650338
http://dx.doi.org/10.1038/s41586-020-2530-3