Cargando…
The emergence of the brain non-CpG methylation system in vertebrates
Mammalian brains feature exceptionally high levels of non-CpG DNA methylation alongside the canonical form of CpG methylation. Non-CpG methylation plays a critical regulatory role in cognitive function, which is mediated by the binding of MeCP2, the transcriptional regulator that when mutated causes...
Autores principales: | de Mendoza, Alex, Poppe, Daniel, Buckberry, Sam, Pflueger, Jahnvi, Albertin, Caroline B., Daish, Tasman, Bertrand, Stephanie, de la Calle-Mustienes, Elisa, Gomez-Skarmeta, Jose Luis, Nery, Joseph R., Ecker, Joseph R., Baer, Boris, Ragsdale, Clifton W., Grützner, Frank, Escriva, Hector, Venkatesh, Byrappa, Bogdanovic, Ozren, Lister, Ryan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116863/ https://www.ncbi.nlm.nih.gov/pubmed/33462491 http://dx.doi.org/10.1038/s41559-020-01371-2 |
Ejemplares similares
-
Genome-wide epigenetic cross-talk between DNA methylation and H3K27me3 in zebrafish embryos
por: de la Calle Mustienes, Elisa, et al.
Publicado: (2015) -
Depletion of Foxk transcription factors causes genome-wide transcriptional misregulation and developmental arrest in zebrafish embryos
por: Geng, Fan-Suo, et al.
Publicado: (2020) -
Capture of a functionally active methyl-CpG binding domain by an arthropod retrotransposon family
por: de Mendoza, Alex, et al.
Publicado: (2019) -
Large-scale manipulation of promoter DNA methylation reveals context-specific transcriptional responses and stability
por: de Mendoza, Alex, et al.
Publicado: (2022) -
Convergent evolution of a vertebrate-like methylome in a marine sponge
por: de Mendoza, Alex, et al.
Publicado: (2019)