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Sero-prevalence, cross-species infection and serological determinants of prevalence of Bovine Coronavirus in Cattle, Sheep and Goats in Ghana
Cattle, goats and sheep are dominant livestock species in sub-Saharan Africa, with sometimes limited information on the prevalence of major infectious diseases. Restrictions due to notifiable epizootics complicate the exchange of samples in surveillance studies and suggest that laboratory capacities...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117134/ https://www.ncbi.nlm.nih.gov/pubmed/31928696 http://dx.doi.org/10.1016/j.vetmic.2019.108544 |
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author | Burimuah, Vitus Sylverken, Augustina Owusu, Michael El-Duah, Philip Yeboah, Richmond Lamptey, Jones Frimpong, Yaw Oppong Agbenyega, Olivia Folitse, Raphael Tasiame, William Emikpe, Benjamin Owiredu, Eddie-Williams Oppong, Samuel Adu-Sarkodie, Yaw Drosten, Christian |
author_facet | Burimuah, Vitus Sylverken, Augustina Owusu, Michael El-Duah, Philip Yeboah, Richmond Lamptey, Jones Frimpong, Yaw Oppong Agbenyega, Olivia Folitse, Raphael Tasiame, William Emikpe, Benjamin Owiredu, Eddie-Williams Oppong, Samuel Adu-Sarkodie, Yaw Drosten, Christian |
author_sort | Burimuah, Vitus |
collection | PubMed |
description | Cattle, goats and sheep are dominant livestock species in sub-Saharan Africa, with sometimes limited information on the prevalence of major infectious diseases. Restrictions due to notifiable epizootics complicate the exchange of samples in surveillance studies and suggest that laboratory capacities should be established domestically. Bovine Coronavirus (BCoV) causes mainly enteric disease in cattle. Spillover to small ruminants is possible. Here we established BCoV serology based on a recombinant immunofluorescence assay for cattle, goats and sheep, and studied the seroprevalence of BCoV in these species in four different locations in the Greater Accra, Volta, Upper East, and Northern provinces of Ghana. The whole sampling and testing was organized and conducted by a veterinary school in Kumasi, Ashanti Region of Ghana. Among sampled sheep (n = 102), goats (n = 66), and cattle (n = 1495), the seroprevalence rates were 25.8 %, 43.1 % and 55.8 %. For cattle, seroprevalence was significantly higher on larger farms (82.2 % vs 17.8 %, comparing farms with >50 or <50 animals; p = 0.027). Highest prevalence was seen in the Northern province with dry climate, but no significant trend following the north-south gradient of sampling sites was detected. Our study identifies a considerable seroprevalence for BCoV in Ghana and provides further support for the spillover of BCoV to small ruminants in settings with mixed husbandry and limited separation between species. |
format | Online Article Text |
id | pubmed-7117134 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71171342020-04-02 Sero-prevalence, cross-species infection and serological determinants of prevalence of Bovine Coronavirus in Cattle, Sheep and Goats in Ghana Burimuah, Vitus Sylverken, Augustina Owusu, Michael El-Duah, Philip Yeboah, Richmond Lamptey, Jones Frimpong, Yaw Oppong Agbenyega, Olivia Folitse, Raphael Tasiame, William Emikpe, Benjamin Owiredu, Eddie-Williams Oppong, Samuel Adu-Sarkodie, Yaw Drosten, Christian Vet Microbiol Article Cattle, goats and sheep are dominant livestock species in sub-Saharan Africa, with sometimes limited information on the prevalence of major infectious diseases. Restrictions due to notifiable epizootics complicate the exchange of samples in surveillance studies and suggest that laboratory capacities should be established domestically. Bovine Coronavirus (BCoV) causes mainly enteric disease in cattle. Spillover to small ruminants is possible. Here we established BCoV serology based on a recombinant immunofluorescence assay for cattle, goats and sheep, and studied the seroprevalence of BCoV in these species in four different locations in the Greater Accra, Volta, Upper East, and Northern provinces of Ghana. The whole sampling and testing was organized and conducted by a veterinary school in Kumasi, Ashanti Region of Ghana. Among sampled sheep (n = 102), goats (n = 66), and cattle (n = 1495), the seroprevalence rates were 25.8 %, 43.1 % and 55.8 %. For cattle, seroprevalence was significantly higher on larger farms (82.2 % vs 17.8 %, comparing farms with >50 or <50 animals; p = 0.027). Highest prevalence was seen in the Northern province with dry climate, but no significant trend following the north-south gradient of sampling sites was detected. Our study identifies a considerable seroprevalence for BCoV in Ghana and provides further support for the spillover of BCoV to small ruminants in settings with mixed husbandry and limited separation between species. Published by Elsevier B.V. 2020-02 2019-12-03 /pmc/articles/PMC7117134/ /pubmed/31928696 http://dx.doi.org/10.1016/j.vetmic.2019.108544 Text en © 2019 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Burimuah, Vitus Sylverken, Augustina Owusu, Michael El-Duah, Philip Yeboah, Richmond Lamptey, Jones Frimpong, Yaw Oppong Agbenyega, Olivia Folitse, Raphael Tasiame, William Emikpe, Benjamin Owiredu, Eddie-Williams Oppong, Samuel Adu-Sarkodie, Yaw Drosten, Christian Sero-prevalence, cross-species infection and serological determinants of prevalence of Bovine Coronavirus in Cattle, Sheep and Goats in Ghana |
title | Sero-prevalence, cross-species infection and serological determinants of prevalence of Bovine Coronavirus in Cattle, Sheep and Goats in Ghana |
title_full | Sero-prevalence, cross-species infection and serological determinants of prevalence of Bovine Coronavirus in Cattle, Sheep and Goats in Ghana |
title_fullStr | Sero-prevalence, cross-species infection and serological determinants of prevalence of Bovine Coronavirus in Cattle, Sheep and Goats in Ghana |
title_full_unstemmed | Sero-prevalence, cross-species infection and serological determinants of prevalence of Bovine Coronavirus in Cattle, Sheep and Goats in Ghana |
title_short | Sero-prevalence, cross-species infection and serological determinants of prevalence of Bovine Coronavirus in Cattle, Sheep and Goats in Ghana |
title_sort | sero-prevalence, cross-species infection and serological determinants of prevalence of bovine coronavirus in cattle, sheep and goats in ghana |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117134/ https://www.ncbi.nlm.nih.gov/pubmed/31928696 http://dx.doi.org/10.1016/j.vetmic.2019.108544 |
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