Natural infection with the porcine respiratory coronavirus induces protective lactogenic immunity against transmissible gastroenteritis

Our objective was to evaluate the level of passive protection against transmissible gastroenteritis (TGE) among 57 newborn piglets nursing from seven seropositive sows previously naturally infected with porcine respiratory coronavirus (PRCV). After challenge exposure we observed mortality rates of 4...

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Autores principales: Bernard, S., Bottreau, E., Aynaud, J.M., Have, P., Szymansky, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1989
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117187/
https://www.ncbi.nlm.nih.gov/pubmed/2560280
http://dx.doi.org/10.1016/0378-1135(89)90013-8
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author Bernard, S.
Bottreau, E.
Aynaud, J.M.
Have, P.
Szymansky, J.
author_facet Bernard, S.
Bottreau, E.
Aynaud, J.M.
Have, P.
Szymansky, J.
author_sort Bernard, S.
collection PubMed
description Our objective was to evaluate the level of passive protection against transmissible gastroenteritis (TGE) among 57 newborn piglets nursing from seven seropositive sows previously naturally infected with porcine respiratory coronavirus (PRCV). After challenge exposure we observed mortality rates of 44% for litters of seven PRCV-infected sows, 40% for litters of four sows orally immunized with the attenuated TGEV strain Nouzilly, and 91% for litters of seven seronegative susceptible sows. A blocking ELISA with two appropriate monoclonal antibodies distinguished serological responses of PRCV-infected sows from those of TGEV-immunized sows. The results suggest that natural infection of the sow with PRCV may induce a degree of protective lactogenic immunity against TGE.
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spelling pubmed-71171872020-04-02 Natural infection with the porcine respiratory coronavirus induces protective lactogenic immunity against transmissible gastroenteritis Bernard, S. Bottreau, E. Aynaud, J.M. Have, P. Szymansky, J. Vet Microbiol Article Our objective was to evaluate the level of passive protection against transmissible gastroenteritis (TGE) among 57 newborn piglets nursing from seven seropositive sows previously naturally infected with porcine respiratory coronavirus (PRCV). After challenge exposure we observed mortality rates of 44% for litters of seven PRCV-infected sows, 40% for litters of four sows orally immunized with the attenuated TGEV strain Nouzilly, and 91% for litters of seven seronegative susceptible sows. A blocking ELISA with two appropriate monoclonal antibodies distinguished serological responses of PRCV-infected sows from those of TGEV-immunized sows. The results suggest that natural infection of the sow with PRCV may induce a degree of protective lactogenic immunity against TGE. Published by Elsevier B.V. 1989-11 2002-11-12 /pmc/articles/PMC7117187/ /pubmed/2560280 http://dx.doi.org/10.1016/0378-1135(89)90013-8 Text en Copyright © 1989 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Bernard, S.
Bottreau, E.
Aynaud, J.M.
Have, P.
Szymansky, J.
Natural infection with the porcine respiratory coronavirus induces protective lactogenic immunity against transmissible gastroenteritis
title Natural infection with the porcine respiratory coronavirus induces protective lactogenic immunity against transmissible gastroenteritis
title_full Natural infection with the porcine respiratory coronavirus induces protective lactogenic immunity against transmissible gastroenteritis
title_fullStr Natural infection with the porcine respiratory coronavirus induces protective lactogenic immunity against transmissible gastroenteritis
title_full_unstemmed Natural infection with the porcine respiratory coronavirus induces protective lactogenic immunity against transmissible gastroenteritis
title_short Natural infection with the porcine respiratory coronavirus induces protective lactogenic immunity against transmissible gastroenteritis
title_sort natural infection with the porcine respiratory coronavirus induces protective lactogenic immunity against transmissible gastroenteritis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117187/
https://www.ncbi.nlm.nih.gov/pubmed/2560280
http://dx.doi.org/10.1016/0378-1135(89)90013-8
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