Cargando…
Dysentery in calves caused by an atypical strain of Escherichia coli (S102-9)
Dysentery lasting 4–8 days was produced in five 4-day-old colostrum-fed calves, after inoculation with an atypical strain of Escherichia coli S102-9; peak excretion of S102-9 occurred during the period of dysentery. Two calves were killed when clinical signs were most severe and bacteria were seen a...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
1986
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117321/ https://www.ncbi.nlm.nih.gov/pubmed/3535233 http://dx.doi.org/10.1016/0378-1135(86)90053-2 |
_version_ | 1783514343526105088 |
---|---|
author | Chanter, N. Hall, G.A. Bland, A.P. Hayle, A.J. Parsons, K.R. |
author_facet | Chanter, N. Hall, G.A. Bland, A.P. Hayle, A.J. Parsons, K.R. |
author_sort | Chanter, N. |
collection | PubMed |
description | Dysentery lasting 4–8 days was produced in five 4-day-old colostrum-fed calves, after inoculation with an atypical strain of Escherichia coli S102-9; peak excretion of S102-9 occurred during the period of dysentery. Two calves were killed when clinical signs were most severe and bacteria were seen attached to the surfaces of enterocytes in the large intestine; microscopic lesions were seen in these areas. The lesions were identical to those previously reported in a natural outbreak of dysentery in calves, from which E. coli S102-9 was isolated, and to those seen in gnotobiotic calves experimentally infected with S102-9. Reinfection of the three surviving calves 16–20 days later with S102-9 and primary infection of two calves aged 24 and 51 days did not cause dysentery. Four of 659 coliforms isolated from field outbreaks of calf diarrhoea resembled the atypical strain S102-9. These four isolates and S102-9 did not produce heat-stable enterotoxin, but all produced a toxin cytopathic for Vero and HeLa cells. Two of the four isolates were inoculated alone into 4-day-old gnotobiotic calves deprived of colostrum; neither calf developed dysentery but microscopic lesions identical to those produced by S102-9 were detected in the large intestines of both animals. |
format | Online Article Text |
id | pubmed-7117321 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1986 |
publisher | Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71173212020-04-02 Dysentery in calves caused by an atypical strain of Escherichia coli (S102-9) Chanter, N. Hall, G.A. Bland, A.P. Hayle, A.J. Parsons, K.R. Vet Microbiol Article Dysentery lasting 4–8 days was produced in five 4-day-old colostrum-fed calves, after inoculation with an atypical strain of Escherichia coli S102-9; peak excretion of S102-9 occurred during the period of dysentery. Two calves were killed when clinical signs were most severe and bacteria were seen attached to the surfaces of enterocytes in the large intestine; microscopic lesions were seen in these areas. The lesions were identical to those previously reported in a natural outbreak of dysentery in calves, from which E. coli S102-9 was isolated, and to those seen in gnotobiotic calves experimentally infected with S102-9. Reinfection of the three surviving calves 16–20 days later with S102-9 and primary infection of two calves aged 24 and 51 days did not cause dysentery. Four of 659 coliforms isolated from field outbreaks of calf diarrhoea resembled the atypical strain S102-9. These four isolates and S102-9 did not produce heat-stable enterotoxin, but all produced a toxin cytopathic for Vero and HeLa cells. Two of the four isolates were inoculated alone into 4-day-old gnotobiotic calves deprived of colostrum; neither calf developed dysentery but microscopic lesions identical to those produced by S102-9 were detected in the large intestines of both animals. Published by Elsevier B.V. 1986-09 2002-11-13 /pmc/articles/PMC7117321/ /pubmed/3535233 http://dx.doi.org/10.1016/0378-1135(86)90053-2 Text en Copyright © 1986 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Chanter, N. Hall, G.A. Bland, A.P. Hayle, A.J. Parsons, K.R. Dysentery in calves caused by an atypical strain of Escherichia coli (S102-9) |
title | Dysentery in calves caused by an atypical strain of Escherichia coli (S102-9) |
title_full | Dysentery in calves caused by an atypical strain of Escherichia coli (S102-9) |
title_fullStr | Dysentery in calves caused by an atypical strain of Escherichia coli (S102-9) |
title_full_unstemmed | Dysentery in calves caused by an atypical strain of Escherichia coli (S102-9) |
title_short | Dysentery in calves caused by an atypical strain of Escherichia coli (S102-9) |
title_sort | dysentery in calves caused by an atypical strain of escherichia coli (s102-9) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117321/ https://www.ncbi.nlm.nih.gov/pubmed/3535233 http://dx.doi.org/10.1016/0378-1135(86)90053-2 |
work_keys_str_mv | AT chantern dysenteryincalvescausedbyanatypicalstrainofescherichiacolis1029 AT hallga dysenteryincalvescausedbyanatypicalstrainofescherichiacolis1029 AT blandap dysenteryincalvescausedbyanatypicalstrainofescherichiacolis1029 AT hayleaj dysenteryincalvescausedbyanatypicalstrainofescherichiacolis1029 AT parsonskr dysenteryincalvescausedbyanatypicalstrainofescherichiacolis1029 |