Cargando…
Intestinal changes associated with rotavirus and enterotoxigenic Escherichia coli infection in calves
Newborn calves inoculated with rotavirus, enterotoxigenic Escherichia coli (ETEC) serotype 020:K′ × 106′:K99:HNM, either alone or in combination, became depressed, anorectic, diarrhoeic and dehydrated. ETEC did not adhere to the intestine although there was extensive proliferation in the lumen. Only...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
1983
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117409/ https://www.ncbi.nlm.nih.gov/pubmed/6405539 http://dx.doi.org/10.1016/0378-1135(83)90017-2 |
_version_ | 1783514364351873024 |
---|---|
author | Tzipori, S. Smith, M. Halpin, C. Makin, T. Krautil, F. |
author_facet | Tzipori, S. Smith, M. Halpin, C. Makin, T. Krautil, F. |
author_sort | Tzipori, S. |
collection | PubMed |
description | Newborn calves inoculated with rotavirus, enterotoxigenic Escherichia coli (ETEC) serotype 020:K′ × 106′:K99:HNM, either alone or in combination, became depressed, anorectic, diarrhoeic and dehydrated. ETEC did not adhere to the intestine although there was extensive proliferation in the lumen. Only slight mucosal changes were induced by ETEC and the activity of membrane bound lactase remained normal. More severe mucosal damage and a decrease in lactase activity were found in newborn calves inoculated with either rotavirus or rotavirus and ETEC in combination. The most severe clinical illness was found in calves inoculated with both rotavirus and ETEC. Calves inoculated at 1 week of age with either rotavirus or ETEC remained clinically normal. Rotavirus infection produced slight mucosal changes and a reduction of lactase activity. In contrast, colostrum-fed or suckling calves up to 2 weeks old inoculated with both rotavirus and ETEC became clinically affected, showed severe mucosal damage and decreased lactase activity. There was no bacterial adhesion to the intestinal mucosa as observed by immunofluorescent labelling and light microscopy. |
format | Online Article Text |
id | pubmed-7117409 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1983 |
publisher | Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71174092020-04-02 Intestinal changes associated with rotavirus and enterotoxigenic Escherichia coli infection in calves Tzipori, S. Smith, M. Halpin, C. Makin, T. Krautil, F. Vet Microbiol Article Newborn calves inoculated with rotavirus, enterotoxigenic Escherichia coli (ETEC) serotype 020:K′ × 106′:K99:HNM, either alone or in combination, became depressed, anorectic, diarrhoeic and dehydrated. ETEC did not adhere to the intestine although there was extensive proliferation in the lumen. Only slight mucosal changes were induced by ETEC and the activity of membrane bound lactase remained normal. More severe mucosal damage and a decrease in lactase activity were found in newborn calves inoculated with either rotavirus or rotavirus and ETEC in combination. The most severe clinical illness was found in calves inoculated with both rotavirus and ETEC. Calves inoculated at 1 week of age with either rotavirus or ETEC remained clinically normal. Rotavirus infection produced slight mucosal changes and a reduction of lactase activity. In contrast, colostrum-fed or suckling calves up to 2 weeks old inoculated with both rotavirus and ETEC became clinically affected, showed severe mucosal damage and decreased lactase activity. There was no bacterial adhesion to the intestinal mucosa as observed by immunofluorescent labelling and light microscopy. Published by Elsevier B.V. 1983-02 2002-11-13 /pmc/articles/PMC7117409/ /pubmed/6405539 http://dx.doi.org/10.1016/0378-1135(83)90017-2 Text en Copyright © 1983 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Tzipori, S. Smith, M. Halpin, C. Makin, T. Krautil, F. Intestinal changes associated with rotavirus and enterotoxigenic Escherichia coli infection in calves |
title | Intestinal changes associated with rotavirus and enterotoxigenic Escherichia coli infection in calves |
title_full | Intestinal changes associated with rotavirus and enterotoxigenic Escherichia coli infection in calves |
title_fullStr | Intestinal changes associated with rotavirus and enterotoxigenic Escherichia coli infection in calves |
title_full_unstemmed | Intestinal changes associated with rotavirus and enterotoxigenic Escherichia coli infection in calves |
title_short | Intestinal changes associated with rotavirus and enterotoxigenic Escherichia coli infection in calves |
title_sort | intestinal changes associated with rotavirus and enterotoxigenic escherichia coli infection in calves |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117409/ https://www.ncbi.nlm.nih.gov/pubmed/6405539 http://dx.doi.org/10.1016/0378-1135(83)90017-2 |
work_keys_str_mv | AT tziporis intestinalchangesassociatedwithrotavirusandenterotoxigenicescherichiacoliinfectionincalves AT smithm intestinalchangesassociatedwithrotavirusandenterotoxigenicescherichiacoliinfectionincalves AT halpinc intestinalchangesassociatedwithrotavirusandenterotoxigenicescherichiacoliinfectionincalves AT makint intestinalchangesassociatedwithrotavirusandenterotoxigenicescherichiacoliinfectionincalves AT krautilf intestinalchangesassociatedwithrotavirusandenterotoxigenicescherichiacoliinfectionincalves |