Cholesterol 25-hydroxylase negatively regulates porcine intestinal coronavirus replication by the production of 25-hydroxycholesterol

Cholesterol 25-hydroxylase (CH25H) has been shown lately to be a host restriction factor that encodes an enzyme, which catalyzes the oxidized form of cholesterol to 25-hydroxycholesterol (25HC). A series of studies have shown that 25HC activity in hosts plays a vital role in inhibiting viral infecti...

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Detalles Bibliográficos
Autores principales: Zhang, Yunhang, Song, Zhongbao, Wang, Mi, Lan, Min, Zhang, Kuo, Jiang, Ping, Li, Yufeng, Bai, Juan, Wang, XianWei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117535/
https://www.ncbi.nlm.nih.gov/pubmed/30955800
http://dx.doi.org/10.1016/j.vetmic.2019.03.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117535/
https://www.ncbi.nlm.nih.gov/pubmed/30955800
http://dx.doi.org/10.1016/j.vetmic.2019.03.004

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