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Replication-inducible vaccinia virus vectors with enhanced safety in vivo

Vaccinia virus (VACV) has been used extensively as the vaccine against smallpox and as a viral vector for the development of recombinant vaccines and cancer therapies. Replication-competent, non-attenuated VACVs induce strong, long-lived humoral and cell-mediated immune responses and can be effectiv...

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Detalles Bibliográficos
Autores principales: O’Connell, Caitlin M., Jasperse, Brittany, Hagen, Caitlin J., Titong, Allison, Verardi, Paulo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117657/
https://www.ncbi.nlm.nih.gov/pubmed/32240193
http://dx.doi.org/10.1371/journal.pone.0230711

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