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Interleukin-10 contributes to PGE(2) signalling through upregulation of EP4 via SHIP1 and STAT3

Macrophage cells form part of our first line defense against pathogens. Macrophages become activated by microbial products such as lipopolysaccharide (LPS) to produce inflammatory mediators, such as TNFα and other cytokines, which orchestrate the host defense against the pathogen. Once the pathogen...

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Detalles Bibliográficos
Autores principales: Samiea, Abrar, Yoon, Jeff S. J., Cheung, Sylvia T., Chamberlain, Thomas C., Mui, Alice L. -F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117666/
https://www.ncbi.nlm.nih.gov/pubmed/32240179
http://dx.doi.org/10.1371/journal.pone.0230427