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Dysfonction immunitaire induite par la ventilation mécanique

Although mechanical ventilation is an essential support in patients admitted to the intensive care unit, clinical and experimental studies have shown that it could be harmful and could induce lung injury. Pulmonary and immune cells can convert mechanical stimuli into biological signals that will lea...

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Detalles Bibliográficos
Autores principales: Tadié, J. M., Gacouin, A., Le Tulzo, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Paris 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117828/
https://www.ncbi.nlm.nih.gov/pubmed/32288738
http://dx.doi.org/10.1007/s13546-014-0846-4
Descripción
Sumario:Although mechanical ventilation is an essential support in patients admitted to the intensive care unit, clinical and experimental studies have shown that it could be harmful and could induce lung injury. Pulmonary and immune cells can convert mechanical stimuli into biological signals that will lead to inflammation. This sterile inflammation both locally and systemically will cause immunosuppression.