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The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer

Enhanced prostaglandin production promotes the development and progression of cancer. Prostaglandins are generated from arachidonic acid (AA) by the action of cyclooxygenase (COX) isoenzymes. However, how cancer cells are able to maintain an elevated supply of AA for prostaglandin production remains...

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Detalles Bibliográficos
Autores principales: Saliakoura, Maria, Reynoso-Moreno, Inés, Pozzato, Chiara, Rossi Sebastiano, Matteo, Galié, Mirco, Gertsch, Jürg, Konstantinidou, Georgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118021/
https://www.ncbi.nlm.nih.gov/pubmed/32034305
http://dx.doi.org/10.1038/s41388-020-1196-5