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Exosome-transmitted lncRNA UFC1 promotes non-small-cell lung cancer progression by EZH2-mediated epigenetic silencing of PTEN expression

Long non-coding RNAs (LncRNAs) have been suggested as important regulators of cancer development and progression in non-small cell lung cancer (NSCLC). Nevertheless, the biological roles and clinical significance of lncRNA UFC1 in NSCLC remain unclear. We detected the expression of UFC1 in tumor tis...

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Detalles Bibliográficos
Autores principales: Zang, Xueyan, Gu, Jianmei, Zhang, Jiayin, Shi, Hui, Hou, Sinan, Xu, Xueying, Chen, Yanke, Zhang, Yu, Mao, Fei, Qian, Hui, Zhu, Taofeng, Xu, Wenrong, Zhang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118073/
https://www.ncbi.nlm.nih.gov/pubmed/32242003
http://dx.doi.org/10.1038/s41419-020-2409-0